Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05

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Standard

Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05. / Frøsig, Thomas Mørch; Yap, Jiawei; Seremet, Tina; Lyngaa, Rikke; Svane, Inge Marie; Thor Straten, Per; Heemskerk, Mirjam H M; Grotenbreg, Gijsbert M; Hadrup, Sine Reker.

I: Cytometry. Part A, Bind 87, Nr. 10, 10.2015, s. 967-75.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Frøsig, TM, Yap, J, Seremet, T, Lyngaa, R, Svane, IM, Thor Straten, P, Heemskerk, MHM, Grotenbreg, GM & Hadrup, SR 2015, 'Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05', Cytometry. Part A, bind 87, nr. 10, s. 967-75. https://doi.org/10.1002/cyto.a.22689

APA

Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, I. M., Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M., & Hadrup, S. R. (2015). Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05. Cytometry. Part A, 87(10), 967-75. https://doi.org/10.1002/cyto.a.22689

Vancouver

Frøsig TM, Yap J, Seremet T, Lyngaa R, Svane IM, Thor Straten P o.a. Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05. Cytometry. Part A. 2015 okt.;87(10):967-75. https://doi.org/10.1002/cyto.a.22689

Author

Frøsig, Thomas Mørch ; Yap, Jiawei ; Seremet, Tina ; Lyngaa, Rikke ; Svane, Inge Marie ; Thor Straten, Per ; Heemskerk, Mirjam H M ; Grotenbreg, Gijsbert M ; Hadrup, Sine Reker. / Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05. I: Cytometry. Part A. 2015 ; Bind 87, Nr. 10. s. 967-75.

Bibtex

@article{6d1ee9704ff143ad899d4a51b6d72ebd,
title = "Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05",
abstract = "We designed conditional ligands restricted to HLA-B*08:01, -B*35:01, and -B*44:05 and proved the use of a conditional ligand previously designed for HLA-B*15:02 together with HLA-B*15:01. Furthermore, we compared the detection capabilities of specific HLA-B*15:01-restricted T cells using the HLA-B*15:01 and HLA-B*15:02 major histocompatibility complex (MHC) multimers and found remarkable differences in the staining patterns detected by flow cytometry. These new conditional ligands greatly add to the application of MHC-based technologies in the analyses of T-cell recognition as they represent frequently expressed HLA-B molecules. This expansion of conditional ligands is important to allow T-cell detection over a wide range of HLA restrictions, and provide comprehensive understanding of the T-cell recognition in a given context.",
author = "Fr{\o}sig, {Thomas M{\o}rch} and Jiawei Yap and Tina Seremet and Rikke Lyngaa and Svane, {Inge Marie} and {Thor Straten}, Per and Heemskerk, {Mirjam H M} and Grotenbreg, {Gijsbert M} and Hadrup, {Sine Reker}",
note = "{\textcopyright} 2015 International Society for Advancement of Cytometry.",
year = "2015",
month = oct,
doi = "10.1002/cyto.a.22689",
language = "English",
volume = "87",
pages = "967--75",
journal = "Cytometry. Supplement : the journal of the Society for Analytical Cytology",
issn = "1046-7386",
publisher = "JohnWiley & Sons, Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05

AU - Frøsig, Thomas Mørch

AU - Yap, Jiawei

AU - Seremet, Tina

AU - Lyngaa, Rikke

AU - Svane, Inge Marie

AU - Thor Straten, Per

AU - Heemskerk, Mirjam H M

AU - Grotenbreg, Gijsbert M

AU - Hadrup, Sine Reker

N1 - © 2015 International Society for Advancement of Cytometry.

PY - 2015/10

Y1 - 2015/10

N2 - We designed conditional ligands restricted to HLA-B*08:01, -B*35:01, and -B*44:05 and proved the use of a conditional ligand previously designed for HLA-B*15:02 together with HLA-B*15:01. Furthermore, we compared the detection capabilities of specific HLA-B*15:01-restricted T cells using the HLA-B*15:01 and HLA-B*15:02 major histocompatibility complex (MHC) multimers and found remarkable differences in the staining patterns detected by flow cytometry. These new conditional ligands greatly add to the application of MHC-based technologies in the analyses of T-cell recognition as they represent frequently expressed HLA-B molecules. This expansion of conditional ligands is important to allow T-cell detection over a wide range of HLA restrictions, and provide comprehensive understanding of the T-cell recognition in a given context.

AB - We designed conditional ligands restricted to HLA-B*08:01, -B*35:01, and -B*44:05 and proved the use of a conditional ligand previously designed for HLA-B*15:02 together with HLA-B*15:01. Furthermore, we compared the detection capabilities of specific HLA-B*15:01-restricted T cells using the HLA-B*15:01 and HLA-B*15:02 major histocompatibility complex (MHC) multimers and found remarkable differences in the staining patterns detected by flow cytometry. These new conditional ligands greatly add to the application of MHC-based technologies in the analyses of T-cell recognition as they represent frequently expressed HLA-B molecules. This expansion of conditional ligands is important to allow T-cell detection over a wide range of HLA restrictions, and provide comprehensive understanding of the T-cell recognition in a given context.

U2 - 10.1002/cyto.a.22689

DO - 10.1002/cyto.a.22689

M3 - Journal article

C2 - 26033882

VL - 87

SP - 967

EP - 975

JO - Cytometry. Supplement : the journal of the Society for Analytical Cytology

JF - Cytometry. Supplement : the journal of the Society for Analytical Cytology

SN - 1046-7386

IS - 10

ER -

ID: 162497367