De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale

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Standard

De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale. / Lenaers, Guy; Amati-Bonneau, Patrizia; Delettre, Cécile; Chevrollier, Arnaud; Verny, Christophe; Miléa, Dan; Procaccio, Vincent; Bonneau, Dominique; Hamel, Christian; Reynier, Pascal.

I: Medecine Sciences, Bind 26, Nr. 10, 01.10.2010, s. 836-41.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lenaers, G, Amati-Bonneau, P, Delettre, C, Chevrollier, A, Verny, C, Miléa, D, Procaccio, V, Bonneau, D, Hamel, C & Reynier, P 2010, 'De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale', Medecine Sciences, bind 26, nr. 10, s. 836-41. https://doi.org/10.1051/medsci/20102610836

APA

Lenaers, G., Amati-Bonneau, P., Delettre, C., Chevrollier, A., Verny, C., Miléa, D., Procaccio, V., Bonneau, D., Hamel, C., & Reynier, P. (2010). De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale. Medecine Sciences, 26(10), 836-41. https://doi.org/10.1051/medsci/20102610836

Vancouver

Lenaers G, Amati-Bonneau P, Delettre C, Chevrollier A, Verny C, Miléa D o.a. De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale. Medecine Sciences. 2010 okt. 1;26(10):836-41. https://doi.org/10.1051/medsci/20102610836

Author

Lenaers, Guy ; Amati-Bonneau, Patrizia ; Delettre, Cécile ; Chevrollier, Arnaud ; Verny, Christophe ; Miléa, Dan ; Procaccio, Vincent ; Bonneau, Dominique ; Hamel, Christian ; Reynier, Pascal. / De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale. I: Medecine Sciences. 2010 ; Bind 26, Nr. 10. s. 836-41.

Bibtex

@article{d7615618c8984b0ebad6d4bb4369a897,
title = "De la levure aux maladies neurod{\'e}g{\'e}n{\'e}ratives : dix ans d'exploration des pathologies de la dynamique mitochondriale",
abstract = "Ten years ago, OPA1 was identified as the major gene responsible for hereditary optic nerve degeneration, evidencing the first defect in mitochondrial network dynamics as the princeps pathophysiological mechanism in a mitochondriopathy. Later, alterations in other genes involved in mitochondrial fusion or fission, such as MFN2, DRP1 and GDAP1, were also associated with inherited neurological diseases, mainly affecting peripheral nerves. More recently, altered mitochondrial plasticity was also demonstrated in common age-related neurodegenerative disorders, as Alzheimer and Parkinson diseases, thus substantiating the critical role of mitochondrial dynamics in neurons as a key element governing the efficiency of oxidative respiration and its distribution along the axons.",
author = "Guy Lenaers and Patrizia Amati-Bonneau and C{\'e}cile Delettre and Arnaud Chevrollier and Christophe Verny and Dan Mil{\'e}a and Vincent Procaccio and Dominique Bonneau and Christian Hamel and Pascal Reynier",
year = "2010",
month = oct,
day = "1",
doi = "http://dx.doi.org/10.1051/medsci/20102610836",
language = "Fransk",
volume = "26",
pages = "836--41",
journal = "Medecine Sciences",
issn = "0767-0974",
publisher = "E D P Sciences",
number = "10",

}

RIS

TY - JOUR

T1 - De la levure aux maladies neurodégénératives : dix ans d'exploration des pathologies de la dynamique mitochondriale

AU - Lenaers, Guy

AU - Amati-Bonneau, Patrizia

AU - Delettre, Cécile

AU - Chevrollier, Arnaud

AU - Verny, Christophe

AU - Miléa, Dan

AU - Procaccio, Vincent

AU - Bonneau, Dominique

AU - Hamel, Christian

AU - Reynier, Pascal

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Ten years ago, OPA1 was identified as the major gene responsible for hereditary optic nerve degeneration, evidencing the first defect in mitochondrial network dynamics as the princeps pathophysiological mechanism in a mitochondriopathy. Later, alterations in other genes involved in mitochondrial fusion or fission, such as MFN2, DRP1 and GDAP1, were also associated with inherited neurological diseases, mainly affecting peripheral nerves. More recently, altered mitochondrial plasticity was also demonstrated in common age-related neurodegenerative disorders, as Alzheimer and Parkinson diseases, thus substantiating the critical role of mitochondrial dynamics in neurons as a key element governing the efficiency of oxidative respiration and its distribution along the axons.

AB - Ten years ago, OPA1 was identified as the major gene responsible for hereditary optic nerve degeneration, evidencing the first defect in mitochondrial network dynamics as the princeps pathophysiological mechanism in a mitochondriopathy. Later, alterations in other genes involved in mitochondrial fusion or fission, such as MFN2, DRP1 and GDAP1, were also associated with inherited neurological diseases, mainly affecting peripheral nerves. More recently, altered mitochondrial plasticity was also demonstrated in common age-related neurodegenerative disorders, as Alzheimer and Parkinson diseases, thus substantiating the critical role of mitochondrial dynamics in neurons as a key element governing the efficiency of oxidative respiration and its distribution along the axons.

U2 - http://dx.doi.org/10.1051/medsci/20102610836

DO - http://dx.doi.org/10.1051/medsci/20102610836

M3 - Tidsskriftartikel

VL - 26

SP - 836

EP - 841

JO - Medecine Sciences

JF - Medecine Sciences

SN - 0767-0974

IS - 10

ER -

ID: 34112856