C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease

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Standard

C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease. / Zacho, Jeppe; Tybjaerg-Hansen, Anne; Nordestgaard, Børge Grønne.

I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 69, Nr. 4, 2009, s. 442-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Zacho, J, Tybjaerg-Hansen, A & Nordestgaard, BG 2009, 'C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease', Scandinavian Journal of Clinical & Laboratory Investigation, bind 69, nr. 4, s. 442-6. https://doi.org/10.1080/00365510903056015

APA

Zacho, J., Tybjaerg-Hansen, A., & Nordestgaard, B. G. (2009). C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease. Scandinavian Journal of Clinical & Laboratory Investigation, 69(4), 442-6. https://doi.org/10.1080/00365510903056015

Vancouver

Zacho J, Tybjaerg-Hansen A, Nordestgaard BG. C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease. Scandinavian Journal of Clinical & Laboratory Investigation. 2009;69(4):442-6. https://doi.org/10.1080/00365510903056015

Author

Zacho, Jeppe ; Tybjaerg-Hansen, Anne ; Nordestgaard, Børge Grønne. / C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease. I: Scandinavian Journal of Clinical & Laboratory Investigation. 2009 ; Bind 69, Nr. 4. s. 442-6.

Bibtex

@article{9fca45a0835011df928f000ea68e967b,
title = "C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease",
abstract = "We tested whether genetically elevated levels of C-reactive protein (CRP) cause increased risk of ischemic heart disease and ischemic cerebrovascular disease. Levels of CRP >3mg/L, compared with levels <1mg/L, associated with a 1.6- and 1.3-fold increased risk of ischemic heart disease and ischemic cerebrovascular disease. Genotype combinations of the 4 CRP polymorphisms associated with up to a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of up to 32% for ischemic heart disease and up to 25% for ischemic cerebrovascular disease. However, these genotype combinations did not associate with increased risk of ischemic heart and cerebrovascular disease.",
author = "Jeppe Zacho and Anne Tybjaerg-Hansen and Nordestgaard, {B{\o}rge Gr{\o}nne}",
note = "Keywords: C-Reactive Protein; Cerebrovascular Disorders; Humans; Myocardial Ischemia; Risk Factors",
year = "2009",
doi = "10.1080/00365510903056015",
language = "English",
volume = "69",
pages = "442--6",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease

AU - Zacho, Jeppe

AU - Tybjaerg-Hansen, Anne

AU - Nordestgaard, Børge Grønne

N1 - Keywords: C-Reactive Protein; Cerebrovascular Disorders; Humans; Myocardial Ischemia; Risk Factors

PY - 2009

Y1 - 2009

N2 - We tested whether genetically elevated levels of C-reactive protein (CRP) cause increased risk of ischemic heart disease and ischemic cerebrovascular disease. Levels of CRP >3mg/L, compared with levels <1mg/L, associated with a 1.6- and 1.3-fold increased risk of ischemic heart disease and ischemic cerebrovascular disease. Genotype combinations of the 4 CRP polymorphisms associated with up to a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of up to 32% for ischemic heart disease and up to 25% for ischemic cerebrovascular disease. However, these genotype combinations did not associate with increased risk of ischemic heart and cerebrovascular disease.

AB - We tested whether genetically elevated levels of C-reactive protein (CRP) cause increased risk of ischemic heart disease and ischemic cerebrovascular disease. Levels of CRP >3mg/L, compared with levels <1mg/L, associated with a 1.6- and 1.3-fold increased risk of ischemic heart disease and ischemic cerebrovascular disease. Genotype combinations of the 4 CRP polymorphisms associated with up to a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of up to 32% for ischemic heart disease and up to 25% for ischemic cerebrovascular disease. However, these genotype combinations did not associate with increased risk of ischemic heart and cerebrovascular disease.

U2 - 10.1080/00365510903056015

DO - 10.1080/00365510903056015

M3 - Journal article

C2 - 19533498

VL - 69

SP - 442

EP - 446

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 4

ER -

ID: 20569680