Consensus-based semi-quantitative ultrasound scoring system for gout lesions: Results of an OMERACT Delphi process and web-reliability exercise
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Consensus-based semi-quantitative ultrasound scoring system for gout lesions : Results of an OMERACT Delphi process and web-reliability exercise. / Christiansen, Sara Nysom; Filippou, Georgios; Scirè, Carlo Alberto; Balint, Peter V.; Bruyn, George AW; Dalbeth, Nicola; Dejaco, Christian; Sedie, Andrea Delle; Filippucci, Emilio; Hammer, Hilde B.; Iagnocco, Annamaria; Keen, Helen I.; Kissin, Eugene Y.; Koski, Juhani; Mandl, Peter; Martin, Julia; Miguel, Eugenio De; Möller, Ingrid; Naredo, Esperanza; Pineda, Carlos; Schmidt, Wolfgang A.; Stewart, Sarah; Antonietta D'Agostino, Maria; Terslev, Lene; on the behalf of the OMERACT Ultrasound working group.
I: Seminars in Arthritis and Rheumatism, Bind 51, Nr. 3, 2021, s. 644-649.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Consensus-based semi-quantitative ultrasound scoring system for gout lesions
T2 - Results of an OMERACT Delphi process and web-reliability exercise
AU - Christiansen, Sara Nysom
AU - Filippou, Georgios
AU - Scirè, Carlo Alberto
AU - Balint, Peter V.
AU - Bruyn, George AW
AU - Dalbeth, Nicola
AU - Dejaco, Christian
AU - Sedie, Andrea Delle
AU - Filippucci, Emilio
AU - Hammer, Hilde B.
AU - Iagnocco, Annamaria
AU - Keen, Helen I.
AU - Kissin, Eugene Y.
AU - Koski, Juhani
AU - Mandl, Peter
AU - Martin, Julia
AU - Miguel, Eugenio De
AU - Möller, Ingrid
AU - Naredo, Esperanza
AU - Pineda, Carlos
AU - Schmidt, Wolfgang A.
AU - Stewart, Sarah
AU - Antonietta D'Agostino, Maria
AU - Terslev, Lene
AU - on the behalf of the OMERACT Ultrasound working group
PY - 2021
Y1 - 2021
N2 - Objective: This study aimed to develop (1) a new ultrasound definition for aggregates and (2) a semi-quantitative ultrasound scoring system (0–3) for tophus, double contour and aggregates. Furthermore, the intra- and inter-reader reliabilities of both the re-defined aggregates and the semi-quantitative scoring system were assessed using static image exercises. Methods: Thirty-seven rheumatologists were invited. A Delphi process was used for re-defining aggregates and for selecting a semi-quantitative scoring system with >75% agreement obligate for reaching consensus. Subsequently, a web-based exercise on static ultrasound images was conducted in order to assess the reliability of both the re-defined aggregates and the semi-quantitative scoring system. Results: Twenty rheumatologists contributed to all rounds of the Delphi and image exercises. A consensual re-definition of aggregates was obtained after three Delphi rounds but needed an overarching principle for scoring aggregates in patients. A consensus-based semi-quantitative ultrasound scoring system for gout lesions was developed after two Delphi rounds. The re-definition of aggregates showed good intra- and inter-reader reliability (κ-values 0.71 and 0.61). The reliabilities of the scoring system were good for all lesions with slightly higher intra-reader (κ-values 0.74–0.80) than inter-reader reliabilities (κ-values 0.61–0.67). Conclusion: A re-definition of aggregates was obtained with a good reliability when assessing static images. The first consensus-based semi-quantitative ultrasound scoring system for gout-specific lesions was developed with good inter- and intra-reader reliability for all lesions when tested in static images. The next step is to assess the reliabilities when scoring lesions in patients.
AB - Objective: This study aimed to develop (1) a new ultrasound definition for aggregates and (2) a semi-quantitative ultrasound scoring system (0–3) for tophus, double contour and aggregates. Furthermore, the intra- and inter-reader reliabilities of both the re-defined aggregates and the semi-quantitative scoring system were assessed using static image exercises. Methods: Thirty-seven rheumatologists were invited. A Delphi process was used for re-defining aggregates and for selecting a semi-quantitative scoring system with >75% agreement obligate for reaching consensus. Subsequently, a web-based exercise on static ultrasound images was conducted in order to assess the reliability of both the re-defined aggregates and the semi-quantitative scoring system. Results: Twenty rheumatologists contributed to all rounds of the Delphi and image exercises. A consensual re-definition of aggregates was obtained after three Delphi rounds but needed an overarching principle for scoring aggregates in patients. A consensus-based semi-quantitative ultrasound scoring system for gout lesions was developed after two Delphi rounds. The re-definition of aggregates showed good intra- and inter-reader reliability (κ-values 0.71 and 0.61). The reliabilities of the scoring system were good for all lesions with slightly higher intra-reader (κ-values 0.74–0.80) than inter-reader reliabilities (κ-values 0.61–0.67). Conclusion: A re-definition of aggregates was obtained with a good reliability when assessing static images. The first consensus-based semi-quantitative ultrasound scoring system for gout-specific lesions was developed with good inter- and intra-reader reliability for all lesions when tested in static images. The next step is to assess the reliabilities when scoring lesions in patients.
KW - Delphi exercise
KW - Gout
KW - OMERACT
KW - Outcome measure
KW - Reliability
KW - Scoring system
KW - Ultrasound
U2 - 10.1016/j.semarthrit.2020.11.011
DO - 10.1016/j.semarthrit.2020.11.011
M3 - Journal article
C2 - 33468347
AN - SCOPUS:85099558909
VL - 51
SP - 644
EP - 649
JO - Seminars in Arthritis and Rheumatism
JF - Seminars in Arthritis and Rheumatism
SN - 0049-0172
IS - 3
ER -
ID: 256072060