Concanavalin A-induced activation of lymphocytic choriomeningitis virus memory lymphocytes into specifically cytotoxic T cells
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Concanavalin A-induced activation of lymphocytic choriomeningitis virus memory lymphocytes into specifically cytotoxic T cells. / Marker, O; Thomsen, Allan Randrup; Andersen, G T.
I: Acta pathologica et microbiologica Scandinavica. Section C, Immunology, Bind 85C, Nr. 6, 1977, s. 483-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Concanavalin A-induced activation of lymphocytic choriomeningitis virus memory lymphocytes into specifically cytotoxic T cells
AU - Marker, O
AU - Thomsen, Allan Randrup
AU - Andersen, G T
N1 - Keywords: Animals; Concanavalin A; Cytotoxicity, Immunologic; Immunologic Memory; Lymphocyte Activation; Lymphocytic choriomeningitis virus; Mice; Mice, Inbred C3H; Spleen; T-Lymphocytes
PY - 1977
Y1 - 1977
N2 - When spleen cells, which have been primed to Lymphocytic Choriomeningitis (LCM) virus during a primary infection several months previously, are stimulated in vitro with Con A. highly specific secondary cytotoxic effector cells are generated. The degree of cytotoxicity revealed by such Con A-stimulated cells is higher than that of non-incubated spleen cells harvested nine days following the primary infection, and the effect is totally inhibited by anti-theta serum plus complement treatment of the effector cells immediately before the cytotoxic test.
AB - When spleen cells, which have been primed to Lymphocytic Choriomeningitis (LCM) virus during a primary infection several months previously, are stimulated in vitro with Con A. highly specific secondary cytotoxic effector cells are generated. The degree of cytotoxicity revealed by such Con A-stimulated cells is higher than that of non-incubated spleen cells harvested nine days following the primary infection, and the effect is totally inhibited by anti-theta serum plus complement treatment of the effector cells immediately before the cytotoxic test.
M3 - Journal article
C2 - 305190
VL - 85C
SP - 483
EP - 486
JO - Acta Pathologica et Microbiologica Scandinavica - Section C Immunology
JF - Acta Pathologica et Microbiologica Scandinavica - Section C Immunology
SN - 0304-1328
IS - 6
ER -
ID: 9702595