Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine
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Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine. / Hansen, Jakob M; Thomsen, Lise L; Olesen, Jes; Ashina, Messoud.
I: Headache, Bind 51, Nr. 4, 2011, s. 544-53.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine
AU - Hansen, Jakob M
AU - Thomsen, Lise L
AU - Olesen, Jes
AU - Ashina, Messoud
N1 - © 2011 American Headache Society.
PY - 2011
Y1 - 2011
N2 - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.
AB - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.
U2 - http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x
DO - http://dx.doi.org/10.1111/j.1526-4610.2011.01861.x
M3 - Journal article
VL - 51
SP - 544
EP - 553
JO - Headache
JF - Headache
SN - 0017-8748
IS - 4
ER -
ID: 40140730