Anti-Müllerian hormone remains highly expressed in human cumulus cells during the final stages of folliculogenesis
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Anti-Müllerian hormone remains highly expressed in human cumulus cells during the final stages of folliculogenesis. / Grøndahl, M L; Nielsen, M Eilsø; Dal Canto, M B; Fadini, R; Rasmussen, I A; Westergaard, L G; Kristensen, S G; Andersen, Claus Yding.
I: Reproductive BioMedicine Online, Bind 22, Nr. 4, 01.04.2011, s. 389-98.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Anti-Müllerian hormone remains highly expressed in human cumulus cells during the final stages of folliculogenesis
AU - Grøndahl, M L
AU - Nielsen, M Eilsø
AU - Dal Canto, M B
AU - Fadini, R
AU - Rasmussen, I A
AU - Westergaard, L G
AU - Kristensen, S G
AU - Andersen, Claus Yding
N1 - Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
PY - 2011/4/1
Y1 - 2011/4/1
N2 - This study evaluated whether anti-Müllerian hormone (AMH) was differentially expressed in cumulus (CC) and granulosa (GC) cells from large antral and pre-ovulatory follicles collected from individual follicles in women undergoing in-vitro maturation (IVM) or IVF treatment. Expression studies of AMH, AMH receptor 2, FSH receptor, aromatase and androgen receptor were performed in CC in IVM patients where cumulus-oocyte-complex had expanded, CC in IVM patients where cumulus-oocyte-complex remained compacted, GC from immature follicles and CC and GC from IVF patients. Microarray data on corresponding GC and CC from follicles from IVF patients was included. AMH expression was significantly higher in CC than in GC from both mature and immature follicles and in CC from immature follicles than in CC from pre-ovulatory follicles from IVF patients (P
AB - This study evaluated whether anti-Müllerian hormone (AMH) was differentially expressed in cumulus (CC) and granulosa (GC) cells from large antral and pre-ovulatory follicles collected from individual follicles in women undergoing in-vitro maturation (IVM) or IVF treatment. Expression studies of AMH, AMH receptor 2, FSH receptor, aromatase and androgen receptor were performed in CC in IVM patients where cumulus-oocyte-complex had expanded, CC in IVM patients where cumulus-oocyte-complex remained compacted, GC from immature follicles and CC and GC from IVF patients. Microarray data on corresponding GC and CC from follicles from IVF patients was included. AMH expression was significantly higher in CC than in GC from both mature and immature follicles and in CC from immature follicles than in CC from pre-ovulatory follicles from IVF patients (P
U2 - 10.1016/j.rbmo.2010.12.005
DO - 10.1016/j.rbmo.2010.12.005
M3 - Journal article
VL - 22
SP - 389
EP - 398
JO - Reproductive BioMedicine Online
JF - Reproductive BioMedicine Online
SN - 1472-6483
IS - 4
ER -
ID: 34113083