Annotation matters: validating the discovery of cancer drivers
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Annotation matters : validating the discovery of cancer drivers. / Rodríguez-Martínez, Marta; Svejstrup, Jesper Q.
I: Molecular & Cellular Oncology, Bind 7, Nr. 6, 1806679 , 2020.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Annotation matters
T2 - validating the discovery of cancer drivers
AU - Rodríguez-Martínez, Marta
AU - Svejstrup, Jesper Q.
PY - 2020
Y1 - 2020
N2 - Advanced sequencing techniques have helped unveil numerous new, potential cancer driver mutations. However, manual curation and analysis of gene and protein annotation are essential to verify such discoveries. Our recent study of STK19 (Serine Threonine Kinase 19), a previously identified melanoma driver, is a clear example of the importance of such detailed analysis, with both STK19 gene and protein annotations in frequently used databases having been proven incorrect.
AB - Advanced sequencing techniques have helped unveil numerous new, potential cancer driver mutations. However, manual curation and analysis of gene and protein annotation are essential to verify such discoveries. Our recent study of STK19 (Serine Threonine Kinase 19), a previously identified melanoma driver, is a clear example of the importance of such detailed analysis, with both STK19 gene and protein annotations in frequently used databases having been proven incorrect.
U2 - 10.1080/23723556.2020.1806679
DO - 10.1080/23723556.2020.1806679
M3 - Journal article
VL - 7
JO - Molecular & Cellular Oncology
JF - Molecular & Cellular Oncology
SN - 2372-3556
IS - 6
M1 - 1806679
ER -
ID: 331043040