An observational study comparing the SPY-Elite® vs. the SPY-PHI QP System in breast reconstructive surgery
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An observational study comparing the SPY-Elite® vs. the SPY-PHI QP System in breast reconstructive surgery. / Lauritzen, Sophie Elisabeth Krogh; Bredgaard, Rikke; Bonde, Christian; Jensen, Lisa Toft; Damsgaard, Tine M Engberg.
I: Annals of Breast Surgery, Bind 7, 2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - An observational study comparing the SPY-Elite® vs. the SPY-PHI QP System in breast reconstructive surgery
AU - Lauritzen, Sophie Elisabeth Krogh
AU - Bredgaard, Rikke
AU - Bonde, Christian
AU - Jensen, Lisa Toft
AU - Damsgaard, Tine M Engberg
PY - 2022
Y1 - 2022
N2 - Background: Indocyanine green angiography (ICG-A) can be applied to visualize per-operative tissue perfusion. Perfusion cut-off values based on ICG-A are important in guiding the intraoperative decision making. Two modalities able to quantify relative tissue perfusion values exist: the SPY-Elite® and the SPY-PHI QP system. We conducted an observational study comparing the quantitative perfusion values of the SPY-Elite® and the SPY-PHI QP with the postoperative outcomes in breast reconstructive procedures.Methods: Sixteen consecutive patients undergoing breast reconstructive surgery (20 breasts) were included. The SPY-Elite® and the SPY-PHI QP imaging systems were applied simultaneously during surgery. There exists no international consensus on cut-off values, therefore cut-off was set to 33% as previous reported by Moyer et al.Results: Five patients had implant-based breast reconstruction, 4 oncoplastic techniques (volume displacement or replacement), 7 autologous tissues (2 pedicled latissimus dorsi flaps and 5 free deep inferior epigastric artery perforator flaps). In 4/16 cases (25%) results of the imaging systems were unequal in quantifying tissue perfusion. The SPY-PHI QP system yielded a sensitivity of 50%, specificity 77%, positive predictive value 25%, negative predictive value 91% and 73% accuracy. The SPY-Elite® had a sensitivity of 50%, specificity 100%, positive predictive value 100%, negative predictive value 93% and 93% accuracy.Conclusions: Imaging modalities assessing and quantifying real-time tissue perfusion is a valuable tool in breast reconstructive surgery. We tested the SPY-Elite® and the SPY-PHI QP using a perfusion cut-off value of 33%. The results were not comparable in assessing and quantifying tissue perfusion using the chosen cut-off value. Further studies investigating specific cut-off values for the SPY-PHI QP is needed.
AB - Background: Indocyanine green angiography (ICG-A) can be applied to visualize per-operative tissue perfusion. Perfusion cut-off values based on ICG-A are important in guiding the intraoperative decision making. Two modalities able to quantify relative tissue perfusion values exist: the SPY-Elite® and the SPY-PHI QP system. We conducted an observational study comparing the quantitative perfusion values of the SPY-Elite® and the SPY-PHI QP with the postoperative outcomes in breast reconstructive procedures.Methods: Sixteen consecutive patients undergoing breast reconstructive surgery (20 breasts) were included. The SPY-Elite® and the SPY-PHI QP imaging systems were applied simultaneously during surgery. There exists no international consensus on cut-off values, therefore cut-off was set to 33% as previous reported by Moyer et al.Results: Five patients had implant-based breast reconstruction, 4 oncoplastic techniques (volume displacement or replacement), 7 autologous tissues (2 pedicled latissimus dorsi flaps and 5 free deep inferior epigastric artery perforator flaps). In 4/16 cases (25%) results of the imaging systems were unequal in quantifying tissue perfusion. The SPY-PHI QP system yielded a sensitivity of 50%, specificity 77%, positive predictive value 25%, negative predictive value 91% and 73% accuracy. The SPY-Elite® had a sensitivity of 50%, specificity 100%, positive predictive value 100%, negative predictive value 93% and 93% accuracy.Conclusions: Imaging modalities assessing and quantifying real-time tissue perfusion is a valuable tool in breast reconstructive surgery. We tested the SPY-Elite® and the SPY-PHI QP using a perfusion cut-off value of 33%. The results were not comparable in assessing and quantifying tissue perfusion using the chosen cut-off value. Further studies investigating specific cut-off values for the SPY-PHI QP is needed.
M3 - Journal article
VL - 7
JO - Annals of Breast Surgery
JF - Annals of Breast Surgery
SN - 2616-2776
ER -
ID: 344847531