AMPK: A key sensor of fuel and energy status in skeletal muscle
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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AMPK : A key sensor of fuel and energy status in skeletal muscle. / Hardie, D. Grahame; Sakamoto, Kei.
I: Physiology, Bind 21, Nr. 1, 01.02.2006, s. 48-60.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - AMPK
T2 - A key sensor of fuel and energy status in skeletal muscle
AU - Hardie, D. Grahame
AU - Sakamoto, Kei
PY - 2006/2/1
Y1 - 2006/2/1
N2 - Contraction induces marked metabolic changes in muscle, and the AMP-activated protein kinase (AMPK) is a good candidate to explain these effects. Recent work using a muscle-specific knockout of the upstream kinase, LKB1, has confirmed that the LKB1→AMPK cascade is the signaling pathway responsible for many of these effects.
AB - Contraction induces marked metabolic changes in muscle, and the AMP-activated protein kinase (AMPK) is a good candidate to explain these effects. Recent work using a muscle-specific knockout of the upstream kinase, LKB1, has confirmed that the LKB1→AMPK cascade is the signaling pathway responsible for many of these effects.
UR - http://www.scopus.com/inward/record.url?scp=33644943620&partnerID=8YFLogxK
U2 - 10.1152/physiol.00044.2005
DO - 10.1152/physiol.00044.2005
M3 - Review
C2 - 16443822
AN - SCOPUS:33644943620
VL - 21
SP - 48
EP - 60
JO - Physiology
JF - Physiology
SN - 1548-9213
IS - 1
ER -
ID: 239585457