Actin cytoskeletal dynamics in single‐cell wound repair

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Actin cytoskeletal dynamics in single‐cell wound repair. / Ebstrup, Malene Laage; Dias, Catarina; Heitmann, Anne Sofie Busk; Sønder, Stine Lauritzen; Nylandsted, Jesper.

I: International Journal of Molecular Sciences, Bind 22, Nr. 19, 10886, 2021.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Ebstrup, ML, Dias, C, Heitmann, ASB, Sønder, SL & Nylandsted, J 2021, 'Actin cytoskeletal dynamics in single‐cell wound repair', International Journal of Molecular Sciences, bind 22, nr. 19, 10886. https://doi.org/10.3390/ijms221910886

APA

Ebstrup, M. L., Dias, C., Heitmann, A. S. B., Sønder, S. L., & Nylandsted, J. (2021). Actin cytoskeletal dynamics in single‐cell wound repair. International Journal of Molecular Sciences, 22(19), [10886]. https://doi.org/10.3390/ijms221910886

Vancouver

Ebstrup ML, Dias C, Heitmann ASB, Sønder SL, Nylandsted J. Actin cytoskeletal dynamics in single‐cell wound repair. International Journal of Molecular Sciences. 2021;22(19). 10886. https://doi.org/10.3390/ijms221910886

Author

Ebstrup, Malene Laage ; Dias, Catarina ; Heitmann, Anne Sofie Busk ; Sønder, Stine Lauritzen ; Nylandsted, Jesper. / Actin cytoskeletal dynamics in single‐cell wound repair. I: International Journal of Molecular Sciences. 2021 ; Bind 22, Nr. 19.

Bibtex

@article{d890c1fff0044185964ca04ce2810b59,

title = "Actin cytoskeletal dynamics in single‐cell wound repair",

abstract = "The plasma membrane protects the eukaryotic cell from its surroundings and is essential for cell viability; thus, it is crucial that membrane disruptions are repaired quickly to prevent immediate dyshomeostasis and cell death. Accordingly, cells have developed efficient repair mechanisms to rapidly reseal ruptures and reestablish membrane integrity. The cortical actin cytoskeleton plays an instrumental role in both plasma membrane resealing and restructuring in response to damage. Actin directly aids membrane repair or indirectly assists auxiliary repair mechanisms. Studies investigating single‐cell wound repair have often focused on the recruitment and activation of specialized repair machinery, despite the undeniable need for rapid and dynamic cortical actin modulation; thus, the role of the cortical actin cytoskeleton during wound repair has received limited attention. This review aims to provide a comprehensive overview of membrane repair mechanisms directly or indirectly involving cortical actin cytoskeletal remodeling.",

keywords = "Actin dynamics, Cell membrane, Cortical actin cytoskeleton, Mechanosensing, Membrane resealing, Membrane restructuring, Plasma membrane injury, Plasma membrane repair, Single‐cell wound repair, Wound healing",

author = "Ebstrup, {Malene Laage} and Catarina Dias and Heitmann, {Anne Sofie Busk} and S{\o}nder, {Stine Lauritzen} and Jesper Nylandsted",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

doi = "10.3390/ijms221910886",

language = "English",

volume = "22",

journal = "International Journal of Molecular Sciences (CD-ROM)",

issn = "1424-6783",

publisher = "M D P I AG",

number = "19",

}

RIS

TY - JOUR

T1 - Actin cytoskeletal dynamics in single‐cell wound repair

AU - Ebstrup, Malene Laage

AU - Dias, Catarina

AU - Heitmann, Anne Sofie Busk

AU - Sønder, Stine Lauritzen

AU - Nylandsted, Jesper

PY - 2021

Y1 - 2021

N2 - The plasma membrane protects the eukaryotic cell from its surroundings and is essential for cell viability; thus, it is crucial that membrane disruptions are repaired quickly to prevent immediate dyshomeostasis and cell death. Accordingly, cells have developed efficient repair mechanisms to rapidly reseal ruptures and reestablish membrane integrity. The cortical actin cytoskeleton plays an instrumental role in both plasma membrane resealing and restructuring in response to damage. Actin directly aids membrane repair or indirectly assists auxiliary repair mechanisms. Studies investigating single‐cell wound repair have often focused on the recruitment and activation of specialized repair machinery, despite the undeniable need for rapid and dynamic cortical actin modulation; thus, the role of the cortical actin cytoskeleton during wound repair has received limited attention. This review aims to provide a comprehensive overview of membrane repair mechanisms directly or indirectly involving cortical actin cytoskeletal remodeling.

AB - The plasma membrane protects the eukaryotic cell from its surroundings and is essential for cell viability; thus, it is crucial that membrane disruptions are repaired quickly to prevent immediate dyshomeostasis and cell death. Accordingly, cells have developed efficient repair mechanisms to rapidly reseal ruptures and reestablish membrane integrity. The cortical actin cytoskeleton plays an instrumental role in both plasma membrane resealing and restructuring in response to damage. Actin directly aids membrane repair or indirectly assists auxiliary repair mechanisms. Studies investigating single‐cell wound repair have often focused on the recruitment and activation of specialized repair machinery, despite the undeniable need for rapid and dynamic cortical actin modulation; thus, the role of the cortical actin cytoskeleton during wound repair has received limited attention. This review aims to provide a comprehensive overview of membrane repair mechanisms directly or indirectly involving cortical actin cytoskeletal remodeling.

KW - Actin dynamics

KW - Cell membrane

KW - Cortical actin cytoskeleton

KW - Mechanosensing

KW - Membrane resealing

KW - Membrane restructuring

KW - Plasma membrane injury

KW - Plasma membrane repair

KW - Single‐cell wound repair

KW - Wound healing

U2 - 10.3390/ijms221910886

DO - 10.3390/ijms221910886

M3 - Review

C2 - 34639226

AN - SCOPUS:85116586475

VL - 22

JO - International Journal of Molecular Sciences (CD-ROM)

JF - International Journal of Molecular Sciences (CD-ROM)

SN - 1424-6783

IS - 19

M1 - 10886

ER -

ID: 284178662