Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration: a multicenter evaluation
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration : a multicenter evaluation. / Chu, Brian K.; Deming, Michael; Biritwum, Nana-Kwadwo; Bougma, Windtaré R.; Dorkenoo, Améyo M.; El-Setouhy, Maged; Fischer, Peter U.; Gass, Katherine; Peña, Manuel Gonzalez de; Simonsen, Paul Erik.
In: P L o S Neglected Tropical Diseases (Online), Vol. 7, No. 12, e2584, 2013.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration
T2 - a multicenter evaluation
AU - Chu, Brian K.
AU - Deming, Michael
AU - Biritwum, Nana-Kwadwo
AU - Bougma, Windtaré R.
AU - Dorkenoo, Améyo M.
AU - El-Setouhy, Maged
AU - Fischer, Peter U.
AU - Gass, Katherine
AU - Peña, Manuel Gonzalez de
AU - Simonsen, Paul Erik
PY - 2013
Y1 - 2013
N2 - Lymphatic filariasis (LF) is targeted for global elimination through treatment of entire at-risk populations with repeated annual mass drug administration (MDA). Essential for program success is defining and confirming the appropriate endpoint for MDA when transmission is presumed to have reached a level low enough that it cannot be sustained even in the absence of drug intervention. Guidelines advanced by WHO call for a transmission assessment survey (TAS) to determine if MDA can be stopped within an LF evaluation unit (EU) after at least five effective rounds of annual treatment. To test the value and practicality of these guidelines, a multicenter operational research trial was undertaken in 11 countries covering various geographic and epidemiological settings.
AB - Lymphatic filariasis (LF) is targeted for global elimination through treatment of entire at-risk populations with repeated annual mass drug administration (MDA). Essential for program success is defining and confirming the appropriate endpoint for MDA when transmission is presumed to have reached a level low enough that it cannot be sustained even in the absence of drug intervention. Guidelines advanced by WHO call for a transmission assessment survey (TAS) to determine if MDA can be stopped within an LF evaluation unit (EU) after at least five effective rounds of annual treatment. To test the value and practicality of these guidelines, a multicenter operational research trial was undertaken in 11 countries covering various geographic and epidemiological settings.
U2 - 10.1371/journal.pntd.0002584
DO - 10.1371/journal.pntd.0002584
M3 - Journal article
C2 - 24340120
VL - 7
JO - P L o S Neglected Tropical Diseases (Online)
JF - P L o S Neglected Tropical Diseases (Online)
SN - 1935-2735
IS - 12
M1 - e2584
ER -
ID: 92326180