Succinct synthesis of saturated hydroxy fatty acids and

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Succinct synthesis of saturated hydroxy fatty acids and. / Kaspersen, Mads Holmgaard; Jenkins, Laura; Dunlop, Julia; Milligan, Graeme; Ulven, Trond.

In: MedChemComm, Vol. 8, No. 6, 2017, p. 1360-1365.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kaspersen, MH, Jenkins, L, Dunlop, J, Milligan, G & Ulven, T 2017, 'Succinct synthesis of saturated hydroxy fatty acids and', MedChemComm, vol. 8, no. 6, pp. 1360-1365. https://doi.org/10.1039/c7md00130d

APA

Kaspersen, M. H., Jenkins, L., Dunlop, J., Milligan, G., & Ulven, T. (2017). Succinct synthesis of saturated hydroxy fatty acids and. MedChemComm, 8(6), 1360-1365. https://doi.org/10.1039/c7md00130d

Vancouver

Kaspersen MH, Jenkins L, Dunlop J, Milligan G, Ulven T. Succinct synthesis of saturated hydroxy fatty acids and. MedChemComm. 2017;8(6):1360-1365. https://doi.org/10.1039/c7md00130d

Author

Kaspersen, Mads Holmgaard ; Jenkins, Laura ; Dunlop, Julia ; Milligan, Graeme ; Ulven, Trond. / Succinct synthesis of saturated hydroxy fatty acids and. In: MedChemComm. 2017 ; Vol. 8, No. 6. pp. 1360-1365.

Bibtex

@article{a079e8ef65534cf3b949ca9045e3953b,
title = "Succinct synthesis of saturated hydroxy fatty acids and",
abstract = "Saturated hydroxy fatty acids make up a class of underexplored lipids with potentially interesting biological activities. We report a succinct and general synthetic route to saturated hydroxy fatty acids hydroxylated at position 6 or higher, and exemplify this with the synthesis of hydroxylauric acids. All regioisomers of hydroxylauric acids were tested on free fatty acid receptors FFA1, FFA4 and GPR84. The results show that the introduction of a hydroxy group and its position have a high impact on receptor activity.",
author = "Kaspersen, {Mads Holmgaard} and Laura Jenkins and Julia Dunlop and Graeme Milligan and Trond Ulven",
year = "2017",
doi = "10.1039/c7md00130d",
language = "English",
volume = "8",
pages = "1360--1365",
journal = "MedChemComm",
issn = "2040-2503",
publisher = "Royal Society of Chemistry",
number = "6",

}

RIS

TY - JOUR

T1 - Succinct synthesis of saturated hydroxy fatty acids and

AU - Kaspersen, Mads Holmgaard

AU - Jenkins, Laura

AU - Dunlop, Julia

AU - Milligan, Graeme

AU - Ulven, Trond

PY - 2017

Y1 - 2017

N2 - Saturated hydroxy fatty acids make up a class of underexplored lipids with potentially interesting biological activities. We report a succinct and general synthetic route to saturated hydroxy fatty acids hydroxylated at position 6 or higher, and exemplify this with the synthesis of hydroxylauric acids. All regioisomers of hydroxylauric acids were tested on free fatty acid receptors FFA1, FFA4 and GPR84. The results show that the introduction of a hydroxy group and its position have a high impact on receptor activity.

AB - Saturated hydroxy fatty acids make up a class of underexplored lipids with potentially interesting biological activities. We report a succinct and general synthetic route to saturated hydroxy fatty acids hydroxylated at position 6 or higher, and exemplify this with the synthesis of hydroxylauric acids. All regioisomers of hydroxylauric acids were tested on free fatty acid receptors FFA1, FFA4 and GPR84. The results show that the introduction of a hydroxy group and its position have a high impact on receptor activity.

U2 - 10.1039/c7md00130d

DO - 10.1039/c7md00130d

M3 - Journal article

C2 - 30108848

VL - 8

SP - 1360

EP - 1365

JO - MedChemComm

JF - MedChemComm

SN - 2040-2503

IS - 6

ER -

ID: 189161226