Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils. / Wilson, Shona; Jones, Frances M.; Fofana, Hassan K. M.; Doucouré, Aissata; Landouré, Aly; Kimani, Gachuhi; Mwatha, Joseph K.; Sacko, Moussa; Vennervald, Birgitte J; Dunne, David W.

In: P L o S Neglected Tropical Diseases (Online), Vol. 7, No. 3, e2149, 2013.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Wilson, S, Jones, FM, Fofana, HKM, Doucouré, A, Landouré, A, Kimani, G, Mwatha, JK, Sacko, M, Vennervald, BJ & Dunne, DW 2013, 'Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils', P L o S Neglected Tropical Diseases (Online), vol. 7, no. 3, e2149. https://doi.org/10.1371/journal.pntd.0002149

APA

Wilson, S., Jones, F. M., Fofana, H. K. M., Doucouré, A., Landouré, A., Kimani, G., Mwatha, J. K., Sacko, M., Vennervald, B. J., & Dunne, D. W. (2013). Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils. P L o S Neglected Tropical Diseases (Online), 7(3), [e2149]. https://doi.org/10.1371/journal.pntd.0002149

Vancouver

Wilson S, Jones FM, Fofana HKM, Doucouré A, Landouré A, Kimani G et al. Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils. P L o S Neglected Tropical Diseases (Online). 2013;7(3). e2149. https://doi.org/10.1371/journal.pntd.0002149

Author

Wilson, Shona ; Jones, Frances M. ; Fofana, Hassan K. M. ; Doucouré, Aissata ; Landouré, Aly ; Kimani, Gachuhi ; Mwatha, Joseph K. ; Sacko, Moussa ; Vennervald, Birgitte J ; Dunne, David W. / Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils. In: P L o S Neglected Tropical Diseases (Online). 2013 ; Vol. 7, No. 3.

Bibtex

@article{0c9e659303a642d699f4577daf0fb1c5,
title = "Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils",
abstract = "IgE specific to worm antigen (SWA) and pre-treatment eosinophil number, are associated with human immunity to re-infection with schistosomes after chemotherapeutic treatment. Treatment significantly elevates circulating IL-5 24-hr post-treatment of Schistosoma mansoni. Here we investigate if praziquantel treatment of human schistosomiasis haematobium also boosts circulating IL-5, the immunological and parasitological factors that predispose to this, and the relationship between these and subsequent immunity to post-treatment re-infection.",
keywords = "Adolescent, Adult, Animals, Anthelmintics, Antigens, Helminth, Child, Child, Preschool, Eosinophils, Female, Humans, Immunoglobulin E, Interleukin-5, Male, Plasma, Praziquantel, Schistosoma haematobium, Schistosomiasis haematobia, Young Adult",
author = "Shona Wilson and Jones, {Frances M.} and Fofana, {Hassan K. M.} and Aissata Doucour{\'e} and Aly Landour{\'e} and Gachuhi Kimani and Mwatha, {Joseph K.} and Moussa Sacko and Vennervald, {Birgitte J} and Dunne, {David W}",
year = "2013",
doi = "10.1371/journal.pntd.0002149",
language = "English",
volume = "7",
journal = "P L o S Neglected Tropical Diseases (Online)",
issn = "1935-2735",
publisher = "Public Library of Science",
number = "3",

}

RIS

TY - JOUR

T1 - Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils

AU - Wilson, Shona

AU - Jones, Frances M.

AU - Fofana, Hassan K. M.

AU - Doucouré, Aissata

AU - Landouré, Aly

AU - Kimani, Gachuhi

AU - Mwatha, Joseph K.

AU - Sacko, Moussa

AU - Vennervald, Birgitte J

AU - Dunne, David W

PY - 2013

Y1 - 2013

N2 - IgE specific to worm antigen (SWA) and pre-treatment eosinophil number, are associated with human immunity to re-infection with schistosomes after chemotherapeutic treatment. Treatment significantly elevates circulating IL-5 24-hr post-treatment of Schistosoma mansoni. Here we investigate if praziquantel treatment of human schistosomiasis haematobium also boosts circulating IL-5, the immunological and parasitological factors that predispose to this, and the relationship between these and subsequent immunity to post-treatment re-infection.

AB - IgE specific to worm antigen (SWA) and pre-treatment eosinophil number, are associated with human immunity to re-infection with schistosomes after chemotherapeutic treatment. Treatment significantly elevates circulating IL-5 24-hr post-treatment of Schistosoma mansoni. Here we investigate if praziquantel treatment of human schistosomiasis haematobium also boosts circulating IL-5, the immunological and parasitological factors that predispose to this, and the relationship between these and subsequent immunity to post-treatment re-infection.

KW - Adolescent

KW - Adult

KW - Animals

KW - Anthelmintics

KW - Antigens, Helminth

KW - Child

KW - Child, Preschool

KW - Eosinophils

KW - Female

KW - Humans

KW - Immunoglobulin E

KW - Interleukin-5

KW - Male

KW - Plasma

KW - Praziquantel

KW - Schistosoma haematobium

KW - Schistosomiasis haematobia

KW - Young Adult

U2 - 10.1371/journal.pntd.0002149

DO - 10.1371/journal.pntd.0002149

M3 - Journal article

C2 - 23556029

VL - 7

JO - P L o S Neglected Tropical Diseases (Online)

JF - P L o S Neglected Tropical Diseases (Online)

SN - 1935-2735

IS - 3

M1 - e2149

ER -

ID: 65707561