Prediction of postpartum blood transfusion – risk factors and recurrence
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Prediction of postpartum blood transfusion – risk factors and recurrence. / Wikkelsø, Anne J; Hjortøe, Sofie; Gerds, Thomas A; Møller, Ann M; Langhoff-Roos, Jens.
In: Journal of Maternal - Fetal & Neonatal Medicine, Vol. 27, No. 16, 11.2014, p. 1661-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Prediction of postpartum blood transfusion – risk factors and recurrence
AU - Wikkelsø, Anne J
AU - Hjortøe, Sofie
AU - Gerds, Thomas A
AU - Møller, Ann M
AU - Langhoff-Roos, Jens
PY - 2014/11
Y1 - 2014/11
N2 - OBJECTIVE: The aim was to find clinically useful risk factors for postpartum transfusion and to assess the joint predictive value in a population of women with a first and second delivery.METHODS: All Danish women with a first and second delivery from January 2001 to September 2009 who gave birth in a hospital that reported transfusion of red blood cells to a national database: A total of 96 545 women were included.RESULTS: Retained placental tissue explained more than all other risk factors in vaginal deliveries. Retained placental tissue at first delivery was associated with postpartum transfusion at a second vaginal delivery, and may also be used as an early predictor in parallel with a history of either placental abruption, postpartum transfusion or caesarean delivery. The positive predictive values of having more than one risk factor was low (2.2%-2.7%).CONCLUSIONS: Prediction of postpartum transfusion is difficult. Retained placental tissue is the strongest predictor of postpartum blood transfusion in vaginal deliveries. Retained placental tissue is usually diagnosed for the first time when the bleeding starts, which limits the clinical value of prediction. We need tools for an early diagnosis of retained placenta to intervene early before transfusion is needed.
AB - OBJECTIVE: The aim was to find clinically useful risk factors for postpartum transfusion and to assess the joint predictive value in a population of women with a first and second delivery.METHODS: All Danish women with a first and second delivery from January 2001 to September 2009 who gave birth in a hospital that reported transfusion of red blood cells to a national database: A total of 96 545 women were included.RESULTS: Retained placental tissue explained more than all other risk factors in vaginal deliveries. Retained placental tissue at first delivery was associated with postpartum transfusion at a second vaginal delivery, and may also be used as an early predictor in parallel with a history of either placental abruption, postpartum transfusion or caesarean delivery. The positive predictive values of having more than one risk factor was low (2.2%-2.7%).CONCLUSIONS: Prediction of postpartum transfusion is difficult. Retained placental tissue is the strongest predictor of postpartum blood transfusion in vaginal deliveries. Retained placental tissue is usually diagnosed for the first time when the bleeding starts, which limits the clinical value of prediction. We need tools for an early diagnosis of retained placenta to intervene early before transfusion is needed.
U2 - 10.3109/14767058.2013.872095
DO - 10.3109/14767058.2013.872095
M3 - Journal article
C2 - 24313457
VL - 27
SP - 1661
EP - 1667
JO - Journal of Maternal-Fetal Medicine
JF - Journal of Maternal-Fetal Medicine
SN - 1476-7058
IS - 16
ER -
ID: 134781215