Physical mapping and cloning of RAD56
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Physical mapping and cloning of RAD56. / Mathiasen, David P; Gallina, Irene; Germann, Susanne Manuela; Hamou, Wissam; Eléouët, Morgane; Thodberg, Sara; Eckert-Boulet, Nadine; Game, John; Lisby, Michael.
In: Gene, Vol. 519, No. 1, 25.04.2013, p. 182-186.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Physical mapping and cloning of RAD56
AU - Mathiasen, David P
AU - Gallina, Irene
AU - Germann, Susanne Manuela
AU - Hamou, Wissam
AU - Eléouët, Morgane
AU - Thodberg, Sara
AU - Eckert-Boulet, Nadine
AU - Game, John
AU - Lisby, Michael
N1 - Copyright © 2013 Elsevier B.V. All rights reserved.
PY - 2013/4/25
Y1 - 2013/4/25
N2 - Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, but not to UV light, suggesting that N-terminal acetylation of specific DNA repair proteins is important for efficient DNA repair.
AB - Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, but not to UV light, suggesting that N-terminal acetylation of specific DNA repair proteins is important for efficient DNA repair.
U2 - 10.1016/j.gene.2013.01.044
DO - 10.1016/j.gene.2013.01.044
M3 - Journal article
C2 - 23403232
VL - 519
SP - 182
EP - 186
JO - Gene
JF - Gene
SN - 0378-1119
IS - 1
ER -
ID: 45275731