Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training

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Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training. / Bonne, Thomas Christian; Doucende, Gregory; Flück, Daniela; Jacobs, Robert A; Nordsborg, Nikolai Baastrup; Robach, Paul; Walther, Guillaume; Lundby, Carsten.

In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 306, No. 10, 2014, p. R752-R760.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bonne, TC, Doucende, G, Flück, D, Jacobs, RA, Nordsborg, NB, Robach, P, Walther, G & Lundby, C 2014, 'Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 306, no. 10, pp. R752-R760. https://doi.org/10.1152/ajpregu.00028.2014

APA

Bonne, T. C., Doucende, G., Flück, D., Jacobs, R. A., Nordsborg, N. B., Robach, P., Walther, G., & Lundby, C. (2014). Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 306(10), R752-R760. https://doi.org/10.1152/ajpregu.00028.2014

Vancouver

Bonne TC, Doucende G, Flück D, Jacobs RA, Nordsborg NB, Robach P et al. Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2014;306(10):R752-R760. https://doi.org/10.1152/ajpregu.00028.2014

Author

Bonne, Thomas Christian ; Doucende, Gregory ; Flück, Daniela ; Jacobs, Robert A ; Nordsborg, Nikolai Baastrup ; Robach, Paul ; Walther, Guillaume ; Lundby, Carsten. / Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training. In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2014 ; Vol. 306, No. 10. pp. R752-R760.

Bibtex

@article{472daadccbde4da984056c9d2c8e91cb,
title = "Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training",
abstract = "With this study we tested the hypothesis that six weeks of endurance training increases maximal cardiac output (Qmax) relatively more by elevating blood volume (BV) than by inducing structural and functional changes within the heart. Nine healthy but untrained volunteers (VO2max 47 ± 5 ml.min(-1).kg(-1)) underwent supervised training (60 min; 4 times weekly at 65% VO2max for six weeks) and Qmax was determined by inert gas re-breathing during cycle ergometer exercise before and after the training period. After the training period, blood volume (determined in duplicates by CO re-breathing) was re-established to pre-training values by phlebotomy and Qmax was quantified again. Resting echography revealed no structural heart adaptations as a consequence of the training intervention. Following the training period, plasma volume (PV), red blood cell volume (RBCV) and BV increased (p",
author = "Bonne, {Thomas Christian} and Gregory Doucende and Daniela Fl{\"u}ck and Jacobs, {Robert A} and Nordsborg, {Nikolai Baastrup} and Paul Robach and Guillaume Walther and Carsten Lundby",
note = "CURIS 2014 NEXS 094",
year = "2014",
doi = "10.1152/ajpregu.00028.2014",
language = "English",
volume = "306",
pages = "R752--R760",
journal = "American Journal of Physiology",
issn = "0363-6119",
publisher = "American Physiological Society",
number = "10",

}

RIS

TY - JOUR

T1 - Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training

AU - Bonne, Thomas Christian

AU - Doucende, Gregory

AU - Flück, Daniela

AU - Jacobs, Robert A

AU - Nordsborg, Nikolai Baastrup

AU - Robach, Paul

AU - Walther, Guillaume

AU - Lundby, Carsten

N1 - CURIS 2014 NEXS 094

PY - 2014

Y1 - 2014

N2 - With this study we tested the hypothesis that six weeks of endurance training increases maximal cardiac output (Qmax) relatively more by elevating blood volume (BV) than by inducing structural and functional changes within the heart. Nine healthy but untrained volunteers (VO2max 47 ± 5 ml.min(-1).kg(-1)) underwent supervised training (60 min; 4 times weekly at 65% VO2max for six weeks) and Qmax was determined by inert gas re-breathing during cycle ergometer exercise before and after the training period. After the training period, blood volume (determined in duplicates by CO re-breathing) was re-established to pre-training values by phlebotomy and Qmax was quantified again. Resting echography revealed no structural heart adaptations as a consequence of the training intervention. Following the training period, plasma volume (PV), red blood cell volume (RBCV) and BV increased (p

AB - With this study we tested the hypothesis that six weeks of endurance training increases maximal cardiac output (Qmax) relatively more by elevating blood volume (BV) than by inducing structural and functional changes within the heart. Nine healthy but untrained volunteers (VO2max 47 ± 5 ml.min(-1).kg(-1)) underwent supervised training (60 min; 4 times weekly at 65% VO2max for six weeks) and Qmax was determined by inert gas re-breathing during cycle ergometer exercise before and after the training period. After the training period, blood volume (determined in duplicates by CO re-breathing) was re-established to pre-training values by phlebotomy and Qmax was quantified again. Resting echography revealed no structural heart adaptations as a consequence of the training intervention. Following the training period, plasma volume (PV), red blood cell volume (RBCV) and BV increased (p

U2 - 10.1152/ajpregu.00028.2014

DO - 10.1152/ajpregu.00028.2014

M3 - Journal article

C2 - 24622974

VL - 306

SP - R752-R760

JO - American Journal of Physiology

JF - American Journal of Physiology

SN - 0363-6119

IS - 10

ER -

ID: 105485190