Molecular motor transport through hollow nanowires

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Molecular motor transport through hollow nanowires. / Lard, Mercy; Ten Siethoff, Lasse; Generosi, Johanna; Månsson, Alf; Linke, Heiner.

In: Nano Letters, Vol. 14, No. 6, 2014, p. 3041-3046.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lard, M, Ten Siethoff, L, Generosi, J, Månsson, A & Linke, H 2014, 'Molecular motor transport through hollow nanowires', Nano Letters, vol. 14, no. 6, pp. 3041-3046. https://doi.org/10.1021/nl404714b

APA

Lard, M., Ten Siethoff, L., Generosi, J., Månsson, A., & Linke, H. (2014). Molecular motor transport through hollow nanowires. Nano Letters, 14(6), 3041-3046. https://doi.org/10.1021/nl404714b

Vancouver

Lard M, Ten Siethoff L, Generosi J, Månsson A, Linke H. Molecular motor transport through hollow nanowires. Nano Letters. 2014;14(6):3041-3046. https://doi.org/10.1021/nl404714b

Author

Lard, Mercy ; Ten Siethoff, Lasse ; Generosi, Johanna ; Månsson, Alf ; Linke, Heiner. / Molecular motor transport through hollow nanowires. In: Nano Letters. 2014 ; Vol. 14, No. 6. pp. 3041-3046.

Bibtex

@article{b453b9a59c9b42b390dc19e0b2920069,
title = "Molecular motor transport through hollow nanowires",
abstract = "Biomolecular motors offer self-propelled, directed transport in designed microscale networks and can potentially replace pump-driven nanofluidics. However, in existing systems, transportation is limited to the two-dimensional plane. Here we demonstrate fully one-dimensional (1D) myosin-driven motion of fluorescent probes (actin filaments) through 80 nm wide, Al2O 3 hollow nanowires of micrometer length. The motor-driven transport is orders of magnitude faster than would be possible by passive diffusion. The system represents a necessary element for advanced devices based on gliding assays, for example, in lab-on-a-chip systems with channel crossings and in pumpless nanosyringes. It may also serve as a scaffold for bottom-up assembly of muscle proteins into ordered contractile units, mimicking the muscle sarcomere.",
keywords = "1D gliding assay, actin, Hollow nanowires, molecular motors, motor proteins, myosin",
author = "Mercy Lard and {Ten Siethoff}, Lasse and Johanna Generosi and Alf M{\aa}nsson and Heiner Linke",
year = "2014",
doi = "10.1021/nl404714b",
language = "English",
volume = "14",
pages = "3041--3046",
journal = "Nano Letters",
issn = "1530-6984",
publisher = "American Chemical Society",
number = "6",

}

RIS

TY - JOUR

T1 - Molecular motor transport through hollow nanowires

AU - Lard, Mercy

AU - Ten Siethoff, Lasse

AU - Generosi, Johanna

AU - Månsson, Alf

AU - Linke, Heiner

PY - 2014

Y1 - 2014

N2 - Biomolecular motors offer self-propelled, directed transport in designed microscale networks and can potentially replace pump-driven nanofluidics. However, in existing systems, transportation is limited to the two-dimensional plane. Here we demonstrate fully one-dimensional (1D) myosin-driven motion of fluorescent probes (actin filaments) through 80 nm wide, Al2O 3 hollow nanowires of micrometer length. The motor-driven transport is orders of magnitude faster than would be possible by passive diffusion. The system represents a necessary element for advanced devices based on gliding assays, for example, in lab-on-a-chip systems with channel crossings and in pumpless nanosyringes. It may also serve as a scaffold for bottom-up assembly of muscle proteins into ordered contractile units, mimicking the muscle sarcomere.

AB - Biomolecular motors offer self-propelled, directed transport in designed microscale networks and can potentially replace pump-driven nanofluidics. However, in existing systems, transportation is limited to the two-dimensional plane. Here we demonstrate fully one-dimensional (1D) myosin-driven motion of fluorescent probes (actin filaments) through 80 nm wide, Al2O 3 hollow nanowires of micrometer length. The motor-driven transport is orders of magnitude faster than would be possible by passive diffusion. The system represents a necessary element for advanced devices based on gliding assays, for example, in lab-on-a-chip systems with channel crossings and in pumpless nanosyringes. It may also serve as a scaffold for bottom-up assembly of muscle proteins into ordered contractile units, mimicking the muscle sarcomere.

KW - 1D gliding assay

KW - actin

KW - Hollow nanowires

KW - molecular motors

KW - motor proteins

KW - myosin

U2 - 10.1021/nl404714b

DO - 10.1021/nl404714b

M3 - Journal article

C2 - 24874101

AN - SCOPUS:84902250949

VL - 14

SP - 3041

EP - 3046

JO - Nano Letters

JF - Nano Letters

SN - 1530-6984

IS - 6

ER -

ID: 131888694