Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells

Research output: Contribution to journal › Journal article › Research › peer-review

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Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells. / Kappe, Camilla; Patrone, Cesare; Holst, Jens Juul; Zhang, Qimin; Sjöholm, Ake.

In: Journal of Gastroenterology, Vol. 48, No. 3, 03.2013, p. 322-32.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kappe, C, Patrone, C, Holst, JJ, Zhang, Q & Sjöholm, A 2013, 'Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells', Journal of Gastroenterology, vol. 48, no. 3, pp. 322-32. https://doi.org/10.1007/s00535-012-0637-5

APA

Kappe, C., Patrone, C., Holst, J. J., Zhang, Q., & Sjöholm, A. (2013). Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells. Journal of Gastroenterology, 48(3), 322-32. https://doi.org/10.1007/s00535-012-0637-5

Vancouver

Kappe C, Patrone C, Holst JJ, Zhang Q, Sjöholm A. Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells. Journal of Gastroenterology. 2013 Mar;48(3):322-32. https://doi.org/10.1007/s00535-012-0637-5

Author

Kappe, Camilla ; Patrone, Cesare ; Holst, Jens Juul ; Zhang, Qimin ; Sjöholm, Ake. / Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells. In: Journal of Gastroenterology. 2013 ; Vol. 48, No. 3. pp. 322-32.

Bibtex

@article{bb11941123d344ac913c02bf851459fd,
title = "Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells",
abstract = "Metformin is the most frequently prescribed drug for treatment of type 2 diabetes. It improves insulin resistance and glycemia by reducing hepatic gluconeogenesis. In addition, diabetic patients on metformin therapy have elevated levels of the insulinotropic hormone glucagon-like peptide-1 (GLP-1) and metformin has been shown to regulate the expression of the GLP-1R in the pancreas.",
author = "Camilla Kappe and Cesare Patrone and Holst, {Jens Juul} and Qimin Zhang and Ake Sj{\"o}holm",
year = "2013",
month = mar,
doi = "10.1007/s00535-012-0637-5",
language = "English",
volume = "48",
pages = "322--32",
journal = "Journal of Gastroenterology",
issn = "0944-1174",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells

AU - Kappe, Camilla

AU - Patrone, Cesare

AU - Holst, Jens Juul

AU - Zhang, Qimin

AU - Sjöholm, Ake

PY - 2013/3

Y1 - 2013/3

N2 - Metformin is the most frequently prescribed drug for treatment of type 2 diabetes. It improves insulin resistance and glycemia by reducing hepatic gluconeogenesis. In addition, diabetic patients on metformin therapy have elevated levels of the insulinotropic hormone glucagon-like peptide-1 (GLP-1) and metformin has been shown to regulate the expression of the GLP-1R in the pancreas.

AB - Metformin is the most frequently prescribed drug for treatment of type 2 diabetes. It improves insulin resistance and glycemia by reducing hepatic gluconeogenesis. In addition, diabetic patients on metformin therapy have elevated levels of the insulinotropic hormone glucagon-like peptide-1 (GLP-1) and metformin has been shown to regulate the expression of the GLP-1R in the pancreas.

U2 - 10.1007/s00535-012-0637-5

DO - 10.1007/s00535-012-0637-5

M3 - Journal article

C2 - 22850868

VL - 48

SP - 322

EP - 332

JO - Journal of Gastroenterology

JF - Journal of Gastroenterology

SN - 0944-1174

IS - 3

ER -

ID: 45840439