Fast diffusion tensor imaging and tractography of the whole cervical spinal cord using point spread function corrected echo planar imaging
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Fast diffusion tensor imaging and tractography of the whole cervical spinal cord using point spread function corrected echo planar imaging. / Lundell, Hans Magnus Henrik; Barthelemy, Dorothy; Biering-Sørensen, Fin; Cohen-Adad, Julien; Nielsen, Jens Bo; Dyrby, Tim Bjørn.
In: Magnetic Resonance in Medicine, Vol. 69, No. 1, 2013, p. 144-149.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Fast diffusion tensor imaging and tractography of the whole cervical spinal cord using point spread function corrected echo planar imaging
AU - Lundell, Hans Magnus Henrik
AU - Barthelemy, Dorothy
AU - Biering-Sørensen, Fin
AU - Cohen-Adad, Julien
AU - Nielsen, Jens Bo
AU - Dyrby, Tim Bjørn
N1 - CURIS 2013 NEXS 001
PY - 2013
Y1 - 2013
N2 - Diffusion tensor imaging has been used in a number of spinal cord studies, but severe distortions caused by susceptibility induced field inhomogeneities limit its applicability to investigate small volumes within acceptable acquisition times. A way to evaluate image distortions is to map the point spread function of the voxel intensity in a reference scan. In this study, the point spread function was mapped for an echo-planar imaging sequence in the human cervical spinal cord with isotropic resolution and large field of view. Correction with the point spread function map improved anatomical consistency, and full cervical tractography was thereby possible from a C1 seed region in healthy controls and one individual with spinal cord injury. It is suggested that point spread function mapping of the spinal cord can be used in combination with sequence-based methods for reduction of susceptibility artifacts or in high-field imaging settings where off-resonance effects are pronounced. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.
AB - Diffusion tensor imaging has been used in a number of spinal cord studies, but severe distortions caused by susceptibility induced field inhomogeneities limit its applicability to investigate small volumes within acceptable acquisition times. A way to evaluate image distortions is to map the point spread function of the voxel intensity in a reference scan. In this study, the point spread function was mapped for an echo-planar imaging sequence in the human cervical spinal cord with isotropic resolution and large field of view. Correction with the point spread function map improved anatomical consistency, and full cervical tractography was thereby possible from a C1 seed region in healthy controls and one individual with spinal cord injury. It is suggested that point spread function mapping of the spinal cord can be used in combination with sequence-based methods for reduction of susceptibility artifacts or in high-field imaging settings where off-resonance effects are pronounced. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.
U2 - 10.1002/mrm.24235
DO - 10.1002/mrm.24235
M3 - Journal article
C2 - 22396180
VL - 69
SP - 144
EP - 149
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
SN - 0740-3194
IS - 1
ER -
ID: 40318072