Epithelial tumours of the lacrimal gland: a clinical, histopathological, surgical and oncological survey
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Epithelial tumours of the lacrimal gland : a clinical, histopathological, surgical and oncological survey. / von Holstein, Sarah Linéa; Coupland, Sarah E; Briscoe, Daniel; Le Tourneau, Christophe; Heegaard, Steffen.
In: Acta Ophthalmologica, Vol. 91, No. 3, 05.2013, p. 195-206.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Epithelial tumours of the lacrimal gland
T2 - a clinical, histopathological, surgical and oncological survey
AU - von Holstein, Sarah Linéa
AU - Coupland, Sarah E
AU - Briscoe, Daniel
AU - Le Tourneau, Christophe
AU - Heegaard, Steffen
N1 - © 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.
PY - 2013/5
Y1 - 2013/5
N2 - Epithelial tumours of the lacrimal gland represent a large spectrum of lesions with similarities in clinical signs and symptoms but with different biological behaviour and prognosis. They are rare, but with aggressive malignant potential. Tumours of the lacrimal gland may present with swelling of the lacrimal gland, displacement of the eyeball, reduced eye motility and diplopia. Pain and symptoms of short duration before the first ophthalmic consultation are characteristic of malignant tumours. The histological diagnosis determines the subsequent treatment regimen and provides important clues regarding the prognosis. The purpose of this paper is to describe the various primary epithelial tumours of the lacrimal gland. In the first part of the review, the frequency, demographics, clinical presentation and diagnostic features are described. In the second part, primarily tumour-specific histological characteristics are given. Finally, treatment modalities including surgical procedures and medical oncology as well as prognosis are discussed.
AB - Epithelial tumours of the lacrimal gland represent a large spectrum of lesions with similarities in clinical signs and symptoms but with different biological behaviour and prognosis. They are rare, but with aggressive malignant potential. Tumours of the lacrimal gland may present with swelling of the lacrimal gland, displacement of the eyeball, reduced eye motility and diplopia. Pain and symptoms of short duration before the first ophthalmic consultation are characteristic of malignant tumours. The histological diagnosis determines the subsequent treatment regimen and provides important clues regarding the prognosis. The purpose of this paper is to describe the various primary epithelial tumours of the lacrimal gland. In the first part of the review, the frequency, demographics, clinical presentation and diagnostic features are described. In the second part, primarily tumour-specific histological characteristics are given. Finally, treatment modalities including surgical procedures and medical oncology as well as prognosis are discussed.
KW - Adenocarcinoma
KW - Adenoma, Pleomorphic
KW - Adult
KW - Carcinoma
KW - Carcinoma, Adenoid Cystic
KW - Carcinoma, Mucoepidermoid
KW - Eye Neoplasms
KW - Humans
KW - Lacrimal Apparatus Diseases
KW - Male
KW - Middle Aged
KW - Neoplasms, Glandular and Epithelial
U2 - 10.1111/j.1755-3768.2012.02402.x
DO - 10.1111/j.1755-3768.2012.02402.x
M3 - Journal article
C2 - 22471335
VL - 91
SP - 195
EP - 206
JO - Acta Ophthalmologica
JF - Acta Ophthalmologica
SN - 1755-375X
IS - 3
ER -
ID: 120197499