Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model

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Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model. / Chan, K Y; Gupta, S; de Vries, R; Danser, A H J; Villalón, C M; Muñoz-Islas, E; Maassenvandenbrink, A.

In: British Journal of Pharmacology, Vol. 160, No. 6, 01.07.2010, p. 1316-25.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Chan, KY, Gupta, S, de Vries, R, Danser, AHJ, Villalón, CM, Muñoz-Islas, E & Maassenvandenbrink, A 2010, 'Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model', British Journal of Pharmacology, vol. 160, no. 6, pp. 1316-25. https://doi.org/10.1111/j.1476-5381.2010.00733.x

APA

Chan, K. Y., Gupta, S., de Vries, R., Danser, A. H. J., Villalón, C. M., Muñoz-Islas, E., & Maassenvandenbrink, A. (2010). Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model. British Journal of Pharmacology, 160(6), 1316-25. https://doi.org/10.1111/j.1476-5381.2010.00733.x

Vancouver

Chan KY, Gupta S, de Vries R, Danser AHJ, Villalón CM, Muñoz-Islas E et al. Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model. British Journal of Pharmacology. 2010 Jul 1;160(6):1316-25. https://doi.org/10.1111/j.1476-5381.2010.00733.x

Author

Chan, K Y ; Gupta, S ; de Vries, R ; Danser, A H J ; Villalón, C M ; Muñoz-Islas, E ; Maassenvandenbrink, A. / Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model. In: British Journal of Pharmacology. 2010 ; Vol. 160, No. 6. pp. 1316-25.

Bibtex

@article{6c84dc110fd4410e8f2eb6fd9a372413,
title = "Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model",
abstract = "During migraine, trigeminal nerves may release calcitonin gene-related peptide (CGRP), inducing cranial vasodilatation and central nociception; hence, trigeminal inhibition or blockade of craniovascular CGRP receptors may prevent this vasodilatation and abort migraine headache. Several preclinical studies have shown that glutamate receptor antagonists affect the pathophysiology of migraine. This study investigated whether antagonists of NMDA (ketamine and MK801), AMPA (GYKI52466) and kainate (LY466195) glutamate receptors affected dural vasodilatation induced by alpha-CGRP, capsaicin and periarterial electrical stimulation in rats, using intravital microscopy.",
author = "Chan, {K Y} and S Gupta and {de Vries}, R and Danser, {A H J} and Villal{\'o}n, {C M} and E Mu{\~n}oz-Islas and A Maassenvandenbrink",
year = "2010",
month = jul,
day = "1",
doi = "http://dx.doi.org/10.1111/j.1476-5381.2010.00733.x",
language = "English",
volume = "160",
pages = "1316--25",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
number = "6",

}

RIS

TY - JOUR

T1 - Effects of ionotropic glutamate receptor antagonists on rat dural artery diameter in an intravital microscopy model

AU - Chan, K Y

AU - Gupta, S

AU - de Vries, R

AU - Danser, A H J

AU - Villalón, C M

AU - Muñoz-Islas, E

AU - Maassenvandenbrink, A

PY - 2010/7/1

Y1 - 2010/7/1

N2 - During migraine, trigeminal nerves may release calcitonin gene-related peptide (CGRP), inducing cranial vasodilatation and central nociception; hence, trigeminal inhibition or blockade of craniovascular CGRP receptors may prevent this vasodilatation and abort migraine headache. Several preclinical studies have shown that glutamate receptor antagonists affect the pathophysiology of migraine. This study investigated whether antagonists of NMDA (ketamine and MK801), AMPA (GYKI52466) and kainate (LY466195) glutamate receptors affected dural vasodilatation induced by alpha-CGRP, capsaicin and periarterial electrical stimulation in rats, using intravital microscopy.

AB - During migraine, trigeminal nerves may release calcitonin gene-related peptide (CGRP), inducing cranial vasodilatation and central nociception; hence, trigeminal inhibition or blockade of craniovascular CGRP receptors may prevent this vasodilatation and abort migraine headache. Several preclinical studies have shown that glutamate receptor antagonists affect the pathophysiology of migraine. This study investigated whether antagonists of NMDA (ketamine and MK801), AMPA (GYKI52466) and kainate (LY466195) glutamate receptors affected dural vasodilatation induced by alpha-CGRP, capsaicin and periarterial electrical stimulation in rats, using intravital microscopy.

U2 - http://dx.doi.org/10.1111/j.1476-5381.2010.00733.x

DO - http://dx.doi.org/10.1111/j.1476-5381.2010.00733.x

M3 - Journal article

VL - 160

SP - 1316

EP - 1325

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 6

ER -

ID: 34190925