Early identification and intervention in cerebral palsy
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Early identification and intervention in cerebral palsy. / Herskind, Anna; Greisen, Gorm; Nielsen, Jens Bo.
In: Developmental Medicine and Child Neurology, Vol. 57, No. 1, 2015, p. 29-36.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Early identification and intervention in cerebral palsy
AU - Herskind, Anna
AU - Greisen, Gorm
AU - Nielsen, Jens Bo
N1 - CURIS 2015 NEXS 008
PY - 2015
Y1 - 2015
N2 - Infants with possible cerebral palsy (CP) are commonly assumed to benefit from early diagnosis and early intervention, but substantial evidence for this is lacking. There is no consensus in the literature on a definition of 'early', but this review focuses on interventions initiated within the first 6 months after term age. We cover basic neuroscience, arguing for a beneficial effect of early intervention, and discuss why clinical research to support this convincingly is lacking. We argue that infants offered early intervention in future clinical studies must be identified carefully, and that the intervention should be focused on infants showing early signs of CP to determine an effect of treatment. Such signs may be efficiently detected by a combination of neuroimaging and the General Movements Assessment. We propose a research agenda directed at large-scale identification of infants showing early signs of CP and testing of high-intensity, early interventions.
AB - Infants with possible cerebral palsy (CP) are commonly assumed to benefit from early diagnosis and early intervention, but substantial evidence for this is lacking. There is no consensus in the literature on a definition of 'early', but this review focuses on interventions initiated within the first 6 months after term age. We cover basic neuroscience, arguing for a beneficial effect of early intervention, and discuss why clinical research to support this convincingly is lacking. We argue that infants offered early intervention in future clinical studies must be identified carefully, and that the intervention should be focused on infants showing early signs of CP to determine an effect of treatment. Such signs may be efficiently detected by a combination of neuroimaging and the General Movements Assessment. We propose a research agenda directed at large-scale identification of infants showing early signs of CP and testing of high-intensity, early interventions.
U2 - 10.1111/dmcn.12531
DO - 10.1111/dmcn.12531
M3 - Review
C2 - 25041565
VL - 57
SP - 29
EP - 36
JO - Developmental medicine and child neurology. Supplement
JF - Developmental medicine and child neurology. Supplement
SN - 0419-0238
IS - 1
ER -
ID: 120191536