Direct and indirect economic and health consequences of COPD in Denmark: a national register-based study: 1998-2010
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Direct and indirect economic and health consequences of COPD in Denmark : a national register-based study: 1998-2010. / Løkke, Anders; Hilberg, Ole; Tønnesen, Philip; Ibsen, Rikke; Kjellberg, Jakob; Jennum, Poul.
In: B M J Open, Vol. 4, No. 1, e004069, 2014.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Direct and indirect economic and health consequences of COPD in Denmark
T2 - a national register-based study: 1998-2010
AU - Løkke, Anders
AU - Hilberg, Ole
AU - Tønnesen, Philip
AU - Ibsen, Rikke
AU - Kjellberg, Jakob
AU - Jennum, Poul
PY - 2014
Y1 - 2014
N2 - OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is among the leading causes of morbidity and mortality worldwide, but longitudinal studies of the economic consequences of COPD are scarce. This Danish study evaluated for the first time ever the economic consequences of COPD of an entire nation before and after the diagnosis.SETTING: Records from the Danish National Patient Registry (1998-2010), direct and indirect costs, including frequency of primary and secondary sector contacts and procedures, medication, unemployment benefits and social transfer payments were extracted from national databases.PARTICIPANTS: 131 811 patients with COPD were identified and compared with 131 811 randomly selected controls matched for age, gender, educational level, residence and marital status.PRIMARY AND SECONDARY OUTCOME MEASURES: Direct and indirect economic and health consequences of COPD in Denmark in the time period 1998-2010.RESULTS: Patients with COPD had a poor survival. The average (95% CI) 12-year survival rate was 0.364 (0.364 to 0.368) compared with 0.686 among controls (0.682 to 0.690). COPD was associated with significantly higher rates of health-related contacts, medication use and higher socioeconomic costs. The employment and the income rates of employed patients with COPD were significantly lower compared with controls. The annual net costs, including social transfers were €8572 for patients with COPD. These consequences were present up to 11 years before first-time diagnosis in the secondary healthcare sector and became more pronounced with disease advancement.CONCLUSIONS: This study provides unique national data on direct and indirect costs before and after initial diagnosis with COPD in Denmark as well as mortality, health and economic consequences for the individual and for society. It could be speculated that early identification and intervention might contribute to the solution.
AB - OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is among the leading causes of morbidity and mortality worldwide, but longitudinal studies of the economic consequences of COPD are scarce. This Danish study evaluated for the first time ever the economic consequences of COPD of an entire nation before and after the diagnosis.SETTING: Records from the Danish National Patient Registry (1998-2010), direct and indirect costs, including frequency of primary and secondary sector contacts and procedures, medication, unemployment benefits and social transfer payments were extracted from national databases.PARTICIPANTS: 131 811 patients with COPD were identified and compared with 131 811 randomly selected controls matched for age, gender, educational level, residence and marital status.PRIMARY AND SECONDARY OUTCOME MEASURES: Direct and indirect economic and health consequences of COPD in Denmark in the time period 1998-2010.RESULTS: Patients with COPD had a poor survival. The average (95% CI) 12-year survival rate was 0.364 (0.364 to 0.368) compared with 0.686 among controls (0.682 to 0.690). COPD was associated with significantly higher rates of health-related contacts, medication use and higher socioeconomic costs. The employment and the income rates of employed patients with COPD were significantly lower compared with controls. The annual net costs, including social transfers were €8572 for patients with COPD. These consequences were present up to 11 years before first-time diagnosis in the secondary healthcare sector and became more pronounced with disease advancement.CONCLUSIONS: This study provides unique national data on direct and indirect costs before and after initial diagnosis with COPD in Denmark as well as mortality, health and economic consequences for the individual and for society. It could be speculated that early identification and intervention might contribute to the solution.
U2 - 10.1136/bmjopen-2013-004069
DO - 10.1136/bmjopen-2013-004069
M3 - Journal article
C2 - 24394800
VL - 4
JO - BMJ Open
JF - BMJ Open
SN - 2044-6055
IS - 1
M1 - e004069
ER -
ID: 138216960