Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates. / Mathur, D.; Rana, N.; Olsen, Carl Erik; Parmar, V. S.; Prasad, A. K.

In: Journal of Heterocyclic Chemistry, Vol. 52, No. 3, 2015, p. 701-710.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mathur, D, Rana, N, Olsen, CE, Parmar, VS & Prasad, AK 2015, 'Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates', Journal of Heterocyclic Chemistry, vol. 52, no. 3, pp. 701-710. https://doi.org/10.1002/jhet.2159

APA

Mathur, D., Rana, N., Olsen, C. E., Parmar, V. S., & Prasad, A. K. (2015). Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates. Journal of Heterocyclic Chemistry, 52(3), 701-710. https://doi.org/10.1002/jhet.2159

Vancouver

Mathur D, Rana N, Olsen CE, Parmar VS, Prasad AK. Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates. Journal of Heterocyclic Chemistry. 2015;52(3):701-710. https://doi.org/10.1002/jhet.2159

Author

Mathur, D. ; Rana, N. ; Olsen, Carl Erik ; Parmar, V. S. ; Prasad, A. K. / Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates. In: Journal of Heterocyclic Chemistry. 2015 ; Vol. 52, No. 3. pp. 701-710.

Bibtex

@article{7faf77c2cee448a49c23000a605ee420,
title = "Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates",
abstract = "A small library of thirty-two 2′-triazolyl uridine and 2′-triazolyl-5-methyluridine has been synthesized by Cu(I)-catalyzed condensation of 2′-azido-2′-deoxyuridine and 2′-azido-2′-deoxy-5-methyluridine with different alkynes and aryl propargyl ethers in almost quantitative yields. Triazolo-nucleoside conjugates, which can be evaluated for different biological activity for suitable drug development, were unambiguously identified on the basis of 1H NMR, 13C NMR, IR, and HRMS data analysis. These compounds have been synthesized for the first time and have not been reported in the literature earlier.",
author = "D. Mathur and N. Rana and Olsen, {Carl Erik} and Parmar, {V. S.} and Prasad, {A. K.}",
year = "2015",
doi = "10.1002/jhet.2159",
language = "English",
volume = "52",
pages = "701--710",
journal = "Journal of Heterocyclic Chemistry",
issn = "0022-152X",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Cu(I)-catalyzed efficient synthesis of 2′-Triazolo-nucleoside conjugates

AU - Mathur, D.

AU - Rana, N.

AU - Olsen, Carl Erik

AU - Parmar, V. S.

AU - Prasad, A. K.

PY - 2015

Y1 - 2015

N2 - A small library of thirty-two 2′-triazolyl uridine and 2′-triazolyl-5-methyluridine has been synthesized by Cu(I)-catalyzed condensation of 2′-azido-2′-deoxyuridine and 2′-azido-2′-deoxy-5-methyluridine with different alkynes and aryl propargyl ethers in almost quantitative yields. Triazolo-nucleoside conjugates, which can be evaluated for different biological activity for suitable drug development, were unambiguously identified on the basis of 1H NMR, 13C NMR, IR, and HRMS data analysis. These compounds have been synthesized for the first time and have not been reported in the literature earlier.

AB - A small library of thirty-two 2′-triazolyl uridine and 2′-triazolyl-5-methyluridine has been synthesized by Cu(I)-catalyzed condensation of 2′-azido-2′-deoxyuridine and 2′-azido-2′-deoxy-5-methyluridine with different alkynes and aryl propargyl ethers in almost quantitative yields. Triazolo-nucleoside conjugates, which can be evaluated for different biological activity for suitable drug development, were unambiguously identified on the basis of 1H NMR, 13C NMR, IR, and HRMS data analysis. These compounds have been synthesized for the first time and have not been reported in the literature earlier.

U2 - 10.1002/jhet.2159

DO - 10.1002/jhet.2159

M3 - Journal article

VL - 52

SP - 701

EP - 710

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

SN - 0022-152X

IS - 3

ER -

ID: 147203989