Catalytic-independent roles of UTX-1 in C. elegans development

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Catalytic-independent roles of UTX-1 in C. elegans development. / Vandamme, Julien; Salcini, Anna Elisabetta.

In: Worm, Vol. 2, No. 2, 01.04.2013, p. e22188.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Vandamme, J & Salcini, AE 2013, 'Catalytic-independent roles of UTX-1 in C. elegans development', Worm, vol. 2, no. 2, pp. e22188. https://doi.org/10.4161/worm.22188

APA

Vandamme, J., & Salcini, A. E. (2013). Catalytic-independent roles of UTX-1 in C. elegans development. Worm, 2(2), e22188. https://doi.org/10.4161/worm.22188

Vancouver

Vandamme J, Salcini AE. Catalytic-independent roles of UTX-1 in C. elegans development. Worm. 2013 Apr 1;2(2):e22188. https://doi.org/10.4161/worm.22188

Author

Vandamme, Julien ; Salcini, Anna Elisabetta. / Catalytic-independent roles of UTX-1 in C. elegans development. In: Worm. 2013 ; Vol. 2, No. 2. pp. e22188.

Bibtex

@article{3314e489e3c549038ce7e89472e73293,
title = "Catalytic-independent roles of UTX-1 in C. elegans development",
abstract = "We recently analyzed the functional roles of UTX-1 during development. utx-1 is an essential gene required for the correct embryonic and post-embryonic development of C. elegans, and it displays an H3K27me3 demethylase activity. Rescue experiments demonstrated that the enzymatic activity of UTX-1 is not relevant for its role in development. The phenotypes associated with loss of UTX-1 might, instead, be a result of compromised functions of an UTX-1-containing complex. Here we discuss the possible mechanisms by which UTX-1 contributes to normal development.",
author = "Julien Vandamme and Salcini, {Anna Elisabetta}",
year = "2013",
month = apr,
day = "1",
doi = "10.4161/worm.22188",
language = "English",
volume = "2",
pages = "e22188",
journal = "Worm",
issn = "2162-4046",
publisher = "Landes Bioscience",
number = "2",

}

RIS

TY - JOUR

T1 - Catalytic-independent roles of UTX-1 in C. elegans development

AU - Vandamme, Julien

AU - Salcini, Anna Elisabetta

PY - 2013/4/1

Y1 - 2013/4/1

N2 - We recently analyzed the functional roles of UTX-1 during development. utx-1 is an essential gene required for the correct embryonic and post-embryonic development of C. elegans, and it displays an H3K27me3 demethylase activity. Rescue experiments demonstrated that the enzymatic activity of UTX-1 is not relevant for its role in development. The phenotypes associated with loss of UTX-1 might, instead, be a result of compromised functions of an UTX-1-containing complex. Here we discuss the possible mechanisms by which UTX-1 contributes to normal development.

AB - We recently analyzed the functional roles of UTX-1 during development. utx-1 is an essential gene required for the correct embryonic and post-embryonic development of C. elegans, and it displays an H3K27me3 demethylase activity. Rescue experiments demonstrated that the enzymatic activity of UTX-1 is not relevant for its role in development. The phenotypes associated with loss of UTX-1 might, instead, be a result of compromised functions of an UTX-1-containing complex. Here we discuss the possible mechanisms by which UTX-1 contributes to normal development.

U2 - 10.4161/worm.22188

DO - 10.4161/worm.22188

M3 - Journal article

C2 - 24058866

VL - 2

SP - e22188

JO - Worm

JF - Worm

SN - 2162-4046

IS - 2

ER -

ID: 100984377