Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery: a randomised clinical trial

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery : a randomised clinical trial. / Sibilitz, Kirstine L.; Berg, Selina K.; Rasmussen, Trine B.; Risom, Signe Stelling; Thygesen, Lau C.; Tang, Lars; Hansen, Tina B.; Johansen, Pernille Palm; Gluud, Christian; Lindschou, Jane; Schmid, Jean Paul; Hassager, Christian; Køber, Lars; Taylor, Rod S.; Zwisler, Ann-Dorthe.

In: Heart, Vol. 102, No. 24, 12.2016, p. 1995-2003.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sibilitz, KL, Berg, SK, Rasmussen, TB, Risom, SS, Thygesen, LC, Tang, L, Hansen, TB, Johansen, PP, Gluud, C, Lindschou, J, Schmid, JP, Hassager, C, Køber, L, Taylor, RS & Zwisler, A-D 2016, 'Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery: a randomised clinical trial', Heart, vol. 102, no. 24, pp. 1995-2003. https://doi.org/10.1136/heartjnl-2016-309414

APA

Sibilitz, K. L., Berg, S. K., Rasmussen, T. B., Risom, S. S., Thygesen, L. C., Tang, L., Hansen, T. B., Johansen, P. P., Gluud, C., Lindschou, J., Schmid, J. P., Hassager, C., Køber, L., Taylor, R. S., & Zwisler, A-D. (2016). Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery: a randomised clinical trial. Heart, 102(24), 1995-2003. https://doi.org/10.1136/heartjnl-2016-309414

Vancouver

Sibilitz KL, Berg SK, Rasmussen TB, Risom SS, Thygesen LC, Tang L et al. Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery: a randomised clinical trial. Heart. 2016 Dec;102(24):1995-2003. https://doi.org/10.1136/heartjnl-2016-309414

Author

Sibilitz, Kirstine L. ; Berg, Selina K. ; Rasmussen, Trine B. ; Risom, Signe Stelling ; Thygesen, Lau C. ; Tang, Lars ; Hansen, Tina B. ; Johansen, Pernille Palm ; Gluud, Christian ; Lindschou, Jane ; Schmid, Jean Paul ; Hassager, Christian ; Køber, Lars ; Taylor, Rod S. ; Zwisler, Ann-Dorthe. / Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery : a randomised clinical trial. In: Heart. 2016 ; Vol. 102, No. 24. pp. 1995-2003.

Bibtex

@article{7d88022b0736483a92920a162731ed6a,
title = "Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery: a randomised clinical trial",
abstract = "Objective: The evidence for cardiac rehabilitation after valve surgery remains sparse. Current recommendations are therefore based on patients with ischaemic heart disease. The aim of this randomised clinical trial was to assess the effects of cardiac rehabilitation versus usual care after heart valve surgery.Methods: The trial was an investigator-initiated, randomised superiority trial (The CopenHeartVR trial, VR; valve replacement or repair). We randomised 147 patients after heart valve surgery 1:1 to 12 weeks of cardiac rehabilitation consisting of physical exercise and monthly psycho-educational consultations (intervention) versus usual care without structured physical exercise or psycho-educational consultations (control). Primary outcome was physical capacity measured by VO2 peak and secondary outcome was self-reported mental health measured by Short Form-36.Results: 76% were men, mean age 62 years, with aortic (62%), mitral (36%) or tricuspid/pulmonary valve surgery (2%). Cardiac rehabilitation compared with control had a beneficial effect on VO2 peak at 4 months (24.8 mL/kg/min vs 22.5 mL/kg/min, p=0.045) but did not affect Short Form-36 Mental Component Scale at 6 months (53.7 vs 55.2 points, p=0.40) or the exploratory physical and mental outcomes. Cardiac rehabilitation increased the occurrence of self-reported non-serious adverse events (11/72 vs 3/75, p=0.02).Conclusions: Cardiac rehabilitation after heart valve surgery significantly improves VO2 peak at 4 months but has no effect on mental health and other measures of exercise capacity and self-reported outcomes. Further research is needed to justify cardiac rehabilitation in this patient group.Trial registration number NCT01558765, Results.",
author = "Sibilitz, {Kirstine L.} and Berg, {Selina K.} and Rasmussen, {Trine B.} and Risom, {Signe Stelling} and Thygesen, {Lau C.} and Lars Tang and Hansen, {Tina B.} and Johansen, {Pernille Palm} and Christian Gluud and Jane Lindschou and Schmid, {Jean Paul} and Christian Hassager and Lars K{\o}ber and Taylor, {Rod S.} and Ann-Dorthe Zwisler",
year = "2016",
month = dec,
doi = "10.1136/heartjnl-2016-309414",
language = "English",
volume = "102",
pages = "1995--2003",
journal = "Heart",
issn = "1355-6037",
publisher = "B M J Group",
number = "24",

}

RIS

TY - JOUR

T1 - Cardiac rehabilitation increases physical capacity but not mental health after heart valve surgery

T2 - a randomised clinical trial

AU - Sibilitz, Kirstine L.

AU - Berg, Selina K.

AU - Rasmussen, Trine B.

AU - Risom, Signe Stelling

AU - Thygesen, Lau C.

AU - Tang, Lars

AU - Hansen, Tina B.

AU - Johansen, Pernille Palm

AU - Gluud, Christian

AU - Lindschou, Jane

AU - Schmid, Jean Paul

AU - Hassager, Christian

AU - Køber, Lars

AU - Taylor, Rod S.

AU - Zwisler, Ann-Dorthe

PY - 2016/12

Y1 - 2016/12

N2 - Objective: The evidence for cardiac rehabilitation after valve surgery remains sparse. Current recommendations are therefore based on patients with ischaemic heart disease. The aim of this randomised clinical trial was to assess the effects of cardiac rehabilitation versus usual care after heart valve surgery.Methods: The trial was an investigator-initiated, randomised superiority trial (The CopenHeartVR trial, VR; valve replacement or repair). We randomised 147 patients after heart valve surgery 1:1 to 12 weeks of cardiac rehabilitation consisting of physical exercise and monthly psycho-educational consultations (intervention) versus usual care without structured physical exercise or psycho-educational consultations (control). Primary outcome was physical capacity measured by VO2 peak and secondary outcome was self-reported mental health measured by Short Form-36.Results: 76% were men, mean age 62 years, with aortic (62%), mitral (36%) or tricuspid/pulmonary valve surgery (2%). Cardiac rehabilitation compared with control had a beneficial effect on VO2 peak at 4 months (24.8 mL/kg/min vs 22.5 mL/kg/min, p=0.045) but did not affect Short Form-36 Mental Component Scale at 6 months (53.7 vs 55.2 points, p=0.40) or the exploratory physical and mental outcomes. Cardiac rehabilitation increased the occurrence of self-reported non-serious adverse events (11/72 vs 3/75, p=0.02).Conclusions: Cardiac rehabilitation after heart valve surgery significantly improves VO2 peak at 4 months but has no effect on mental health and other measures of exercise capacity and self-reported outcomes. Further research is needed to justify cardiac rehabilitation in this patient group.Trial registration number NCT01558765, Results.

AB - Objective: The evidence for cardiac rehabilitation after valve surgery remains sparse. Current recommendations are therefore based on patients with ischaemic heart disease. The aim of this randomised clinical trial was to assess the effects of cardiac rehabilitation versus usual care after heart valve surgery.Methods: The trial was an investigator-initiated, randomised superiority trial (The CopenHeartVR trial, VR; valve replacement or repair). We randomised 147 patients after heart valve surgery 1:1 to 12 weeks of cardiac rehabilitation consisting of physical exercise and monthly psycho-educational consultations (intervention) versus usual care without structured physical exercise or psycho-educational consultations (control). Primary outcome was physical capacity measured by VO2 peak and secondary outcome was self-reported mental health measured by Short Form-36.Results: 76% were men, mean age 62 years, with aortic (62%), mitral (36%) or tricuspid/pulmonary valve surgery (2%). Cardiac rehabilitation compared with control had a beneficial effect on VO2 peak at 4 months (24.8 mL/kg/min vs 22.5 mL/kg/min, p=0.045) but did not affect Short Form-36 Mental Component Scale at 6 months (53.7 vs 55.2 points, p=0.40) or the exploratory physical and mental outcomes. Cardiac rehabilitation increased the occurrence of self-reported non-serious adverse events (11/72 vs 3/75, p=0.02).Conclusions: Cardiac rehabilitation after heart valve surgery significantly improves VO2 peak at 4 months but has no effect on mental health and other measures of exercise capacity and self-reported outcomes. Further research is needed to justify cardiac rehabilitation in this patient group.Trial registration number NCT01558765, Results.

U2 - 10.1136/heartjnl-2016-309414

DO - 10.1136/heartjnl-2016-309414

M3 - Journal article

C2 - 27492941

VL - 102

SP - 1995

EP - 2003

JO - Heart

JF - Heart

SN - 1355-6037

IS - 24

ER -

ID: 170082281