Approaches to link RNA secondary structures with splicing regulation

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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Approaches to link RNA secondary structures with splicing regulation. / Plass, Mireya; Eyras, Eduardo.

Spliceosomal Pre-mRNA Splicing. ed. / Klemens J. Hertel . Vol. 1126 Springer Science+Business Media, 2014. p. 341-356 (Methods in Molecular Biology, Vol. 1126).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Harvard

Plass, M & Eyras, E 2014, Approaches to link RNA secondary structures with splicing regulation. in KJ Hertel (ed.), Spliceosomal Pre-mRNA Splicing. vol. 1126, Springer Science+Business Media, Methods in Molecular Biology, vol. 1126, pp. 341-356. https://doi.org/10.1007/978-1-62703-980-2_25

APA

Plass, M., & Eyras, E. (2014). Approaches to link RNA secondary structures with splicing regulation. In K. J. Hertel (Ed.), Spliceosomal Pre-mRNA Splicing (Vol. 1126, pp. 341-356). Springer Science+Business Media. Methods in Molecular Biology Vol. 1126 https://doi.org/10.1007/978-1-62703-980-2_25

Vancouver

Plass M, Eyras E. Approaches to link RNA secondary structures with splicing regulation. In Hertel KJ, editor, Spliceosomal Pre-mRNA Splicing. Vol. 1126. Springer Science+Business Media. 2014. p. 341-356. (Methods in Molecular Biology, Vol. 1126). https://doi.org/10.1007/978-1-62703-980-2_25

Author

Plass, Mireya ; Eyras, Eduardo. / Approaches to link RNA secondary structures with splicing regulation. Spliceosomal Pre-mRNA Splicing. editor / Klemens J. Hertel . Vol. 1126 Springer Science+Business Media, 2014. pp. 341-356 (Methods in Molecular Biology, Vol. 1126).

Bibtex

@inbook{b2ef9201996a4968a53a8c1e86585954,
title = "Approaches to link RNA secondary structures with splicing regulation",
abstract = "In higher eukaryotes, alternative splicing is usually regulated by protein factors, which bind to the pre-mRNA and affect the recognition of splicing signals. There is recent evidence that the secondary structure of the pre-mRNA may also play an important role in this process, either by facilitating or hindering the interaction with factors and small nuclear ribonucleoproteins (snRNPs) that regulate splicing. Moreover, the secondary structure could play a fundamental role in the splicing of yeast species, which lack many of the regulatory splicing factors present in metazoans. This chapter describes the steps in the analysis of the secondary structure of the pre-mRNA and its possible relation to splicing. As a working example, we use the case of yeast and the problem of the recognition of the 3' splice site (3'ss).",
author = "Mireya Plass and Eduardo Eyras",
year = "2014",
doi = "10.1007/978-1-62703-980-2_25",
language = "English",
isbn = "978-1-62703-979-6",
volume = "1126",
series = "Methods in Molecular Biology",
publisher = "Springer Science+Business Media",
pages = "341--356",
editor = "{Hertel }, {Klemens J.}",
booktitle = "Spliceosomal Pre-mRNA Splicing",
address = "Singapore",

}

RIS

TY - CHAP

T1 - Approaches to link RNA secondary structures with splicing regulation

AU - Plass, Mireya

AU - Eyras, Eduardo

PY - 2014

Y1 - 2014

N2 - In higher eukaryotes, alternative splicing is usually regulated by protein factors, which bind to the pre-mRNA and affect the recognition of splicing signals. There is recent evidence that the secondary structure of the pre-mRNA may also play an important role in this process, either by facilitating or hindering the interaction with factors and small nuclear ribonucleoproteins (snRNPs) that regulate splicing. Moreover, the secondary structure could play a fundamental role in the splicing of yeast species, which lack many of the regulatory splicing factors present in metazoans. This chapter describes the steps in the analysis of the secondary structure of the pre-mRNA and its possible relation to splicing. As a working example, we use the case of yeast and the problem of the recognition of the 3' splice site (3'ss).

AB - In higher eukaryotes, alternative splicing is usually regulated by protein factors, which bind to the pre-mRNA and affect the recognition of splicing signals. There is recent evidence that the secondary structure of the pre-mRNA may also play an important role in this process, either by facilitating or hindering the interaction with factors and small nuclear ribonucleoproteins (snRNPs) that regulate splicing. Moreover, the secondary structure could play a fundamental role in the splicing of yeast species, which lack many of the regulatory splicing factors present in metazoans. This chapter describes the steps in the analysis of the secondary structure of the pre-mRNA and its possible relation to splicing. As a working example, we use the case of yeast and the problem of the recognition of the 3' splice site (3'ss).

U2 - 10.1007/978-1-62703-980-2_25

DO - 10.1007/978-1-62703-980-2_25

M3 - Book chapter

C2 - 24549676

SN - 978-1-62703-979-6

VL - 1126

T3 - Methods in Molecular Biology

SP - 341

EP - 356

BT - Spliceosomal Pre-mRNA Splicing

A2 - Hertel , Klemens J.

PB - Springer Science+Business Media

ER -

ID: 120338791