Administration of gentamicin and ampicillin by continuous intravenous infusion to newborn infants during parenteral nutrition.
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Administration of gentamicin and ampicillin by continuous intravenous infusion to newborn infants during parenteral nutrition. / Colding, H; Andersen, G E.
In: Scandinavian Journal of Infectious Diseases, Vol. 14, No. 1, 1982, p. 61-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Administration of gentamicin and ampicillin by continuous intravenous infusion to newborn infants during parenteral nutrition.
AU - Colding, H
AU - Andersen, G E
N1 - Keywords: Amino Acids; Ampicillin; Bacterial Infections; Female; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Parenteral; Male; Parenteral Nutrition
PY - 1982
Y1 - 1982
N2 - Gentamicin and ampicillin were dissolved in an L-amino acid solution especially prepared for newborn infants and infused intravenously over 24 h in 7 babies with serious neonatal surgical problems. Serum concentrations of the antibiotics were maintained rather constant and well above the minimal inhibitory concentration for most bacterial strains. One very sick newborn infant died with overwhelming Klebsiella pneumoniae septicemia. No signs of renal toxicity or ototoxicity were found. The serum amino acids remained within the normal range, except in 1 child with cytomegalovirus infection and liver insufficiency.
AB - Gentamicin and ampicillin were dissolved in an L-amino acid solution especially prepared for newborn infants and infused intravenously over 24 h in 7 babies with serious neonatal surgical problems. Serum concentrations of the antibiotics were maintained rather constant and well above the minimal inhibitory concentration for most bacterial strains. One very sick newborn infant died with overwhelming Klebsiella pneumoniae septicemia. No signs of renal toxicity or ototoxicity were found. The serum amino acids remained within the normal range, except in 1 child with cytomegalovirus infection and liver insufficiency.
M3 - Journal article
C2 - 6803353
VL - 14
SP - 61
EP - 65
JO - Infectious Diseases
JF - Infectious Diseases
SN - 2374-4235
IS - 1
ER -
ID: 8670205