Mads Lerdrup

Mads Lerdrup

Associate Professor


  1. 2024
  2. Published

    Single-cell m6A mapping in vivo using picoMeRIP–seq

    Li, Y., Wang, Y., Vera-Rodriguez, M., Lindeman, L. C., Skuggen, L. E., Rasmussen, E. M. K., Jermstad, I., Khan, S., Fosslie, M., Skuland, T., Indahl, M., Khodeer, S., Klemsdal, E. K., Jin, K. X., Dalen, K. T., Fedorcsak, P., Greggains, G. D., Lerdrup, M., Klungland, A., Au, K. F. & 1 others, Dahl, J. A., 2024, In: Nature Biotechnology. 42, p. 591-596 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate

    Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability

    Bhowmick, Rahul, Mehta, K. P. M., Lerdrup, Mads & Cortez, D., 2023, In: Molecular Cell. 83, 13, p. 2357-2366.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2022
  7. Published

    CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival

    Lier, S., Rein, K. A., Lund, S., Lång, A., Lång, E., Meyer, N., Dutta, A., Anand, S., Nesse, G., Johansen, R., Klungland, A., Rinholm, J., Boe, S., Anand, A., Pollard, S., Lerdrup, Mads & Pandey, D., 2022, In: Neuro-Oncology. 24, S2, p. ii51 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. Published

    Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals

    Sankar, A., Mohammad, F., Sundaramurthy, Arun Kumar, Wang, H., Lerdrup, Mads, Tatar, Tülin & Helin, K., 2022, In: Nature Genetics. 54, p. 754–760

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD+ pathway

    Maynard, S., Hall, A., Galanos, P., Rizza, S., Yamamoto, T., Gram, H. H., Munk, S. H. N., Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm, Lerdrup, Mads, Maya-Mendoza, A. & Bartek, J., 2022, In: Nucleic Acids Research. 50, 17, p. 9948-9965 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    RAD51 protects human cells from transcription-replication conflicts

    Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

    Zonderland, Gijs, Vanzo, R., Gadi, Sampath Amitash, Martín-Doncel, E., Coscia, F., Mund, Andreas, Lerdrup, Mads, Benada, Jan, Boos, D. & Toledo, L., 2022, In: Molecular Cell. 82, 18, p. 3350-3365.e7 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2021
  13. Published

    Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2

    Garribba, L., Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, M. M., Ren, L. & Liu, Ying, 2021, In: Frontiers in Genetics. 12, 695124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes

    Shoaib, Muhammad, Chen, Q., Shi, X., Nair, Nidhi, Prasanna, C., Yang, R., Walter, D., Frederiksen, K. S., Einarsson, H., Svensson, J. P., Liu, C. F., Ekwall, K., Lerdrup, Mads, Nordenskiöld, L. & Sørensen, Claus Storgaard, 2021, In: Nature Communications. 12, 1, 16 p., 4800.

    Research output: Contribution to journalJournal articleResearchpeer-review

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