Mind the gap

Research output: Contribution to journalComment/debateResearchpeer-review

Amino acid deletions are high-risk, high-reward mutations, yet structural consequences are poorly understood. In this issue of Structure, Woods et al. (2023) individually deleted 65 residues from a small α-helical protein, structurally assayed the 17 soluble variants, and developed a computational model of deletion solubility combining Rosetta and AlphaFold2.

Original languageEnglish
Issue number6
Pages (from-to)641-643
Number of pages3
Publication statusPublished - 2023

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Ltd

ID: 360336254