Inspiratory muscle strength and walking capacity in patients with COPD
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Inspiratory muscle strength and walking capacity in patients with COPD. / Kofod, Linette Marie; Hage, Tine; Christiansen, Lene Houmann; Skalkam, Karin; Martinez, Gerd; Godtfredsen, Nina Skavlan; Molsted, Stig.
In: European Clinical Respiratory Journal, Vol. 7, No. 1, 1700086, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Inspiratory muscle strength and walking capacity in patients with COPD
AU - Kofod, Linette Marie
AU - Hage, Tine
AU - Christiansen, Lene Houmann
AU - Skalkam, Karin
AU - Martinez, Gerd
AU - Godtfredsen, Nina Skavlan
AU - Molsted, Stig
PY - 2020
Y1 - 2020
N2 - Purpose: It has been suggested that patients with inspiratory muscle weakness could benefit from specific inspiratory muscle training (IMT). We aimed to examine the frequency of patients with inspiratory muscle weakness in a Danish hospital-based outpatient pulmonary rehabilitation program, and to evaluate the association between inspiratory muscle strength and peripheral muscle strength and walking capacity. Methods: Maximal Inspiratory Pressure (MIP) was assessed in 97 patients with COPD (39 men, 58 women, mean age years 70 ± 9, forced expiratory volume in 1 s ((FEV1) = 35 ± 10% pred.). The impact of MIP on knee-extension strength, walking distance, and symptom burden was evaluated using multiple linear regression analyses. Results: The MIP of the patients with COPD was 63 (95% CI 59; 67) cmH2O and it was significantly reduced compared to gender and age-matched reference values 76 (95% CI 73; 79) cmH2O (p < 0.001). Seven patients (7.2%) were under the lower limit of normal. MIP was negatively correlated with increasing age, female gender, decreasing knee-extension strength and lower FEV1% pred. Walking distance was associated with knee-extension strength and it was not associated with MIP. Conclusion: Maximal inspiratory pressure was reduced in patients with COPD but only a few patients had a weak MIP. Whilst MIP was associated with leg muscle strength, it was not associated with walking distance or symptoms.
AB - Purpose: It has been suggested that patients with inspiratory muscle weakness could benefit from specific inspiratory muscle training (IMT). We aimed to examine the frequency of patients with inspiratory muscle weakness in a Danish hospital-based outpatient pulmonary rehabilitation program, and to evaluate the association between inspiratory muscle strength and peripheral muscle strength and walking capacity. Methods: Maximal Inspiratory Pressure (MIP) was assessed in 97 patients with COPD (39 men, 58 women, mean age years 70 ± 9, forced expiratory volume in 1 s ((FEV1) = 35 ± 10% pred.). The impact of MIP on knee-extension strength, walking distance, and symptom burden was evaluated using multiple linear regression analyses. Results: The MIP of the patients with COPD was 63 (95% CI 59; 67) cmH2O and it was significantly reduced compared to gender and age-matched reference values 76 (95% CI 73; 79) cmH2O (p < 0.001). Seven patients (7.2%) were under the lower limit of normal. MIP was negatively correlated with increasing age, female gender, decreasing knee-extension strength and lower FEV1% pred. Walking distance was associated with knee-extension strength and it was not associated with MIP. Conclusion: Maximal inspiratory pressure was reduced in patients with COPD but only a few patients had a weak MIP. Whilst MIP was associated with leg muscle strength, it was not associated with walking distance or symptoms.
KW - chronic obstructive pulmonary disease
KW - Maximal inspiratory strength
KW - physiotherapy
KW - quadriceps strength
KW - walking distance
U2 - 10.1080/20018525.2019.1700086
DO - 10.1080/20018525.2019.1700086
M3 - Journal article
C2 - 31853341
AN - SCOPUS:85082729816
VL - 7
JO - European Clinical Respiratory Journal
JF - European Clinical Respiratory Journal
SN - 2001-8525
IS - 1
M1 - 1700086
ER -
ID: 253149172