In vivo studies of peritendinous tissue in exercise
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
In vivo studies of peritendinous tissue in exercise. / Kjaer, M; Langberg, Henning; Skovgaard, D; Olesen, J; Bülow, J; Krogsgaard, M; Boushel, R.
In: Scandinavian Journal of Medicine & Science in Sports, Vol. 10, No. 6, 12.2000, p. 326-31.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - In vivo studies of peritendinous tissue in exercise
AU - Kjaer, M
AU - Langberg, Henning
AU - Skovgaard, D
AU - Olesen, J
AU - Bülow, J
AU - Krogsgaard, M
AU - Boushel, R
PY - 2000/12
Y1 - 2000/12
N2 - Soft tissue injury of tendons represents a major problem within sports medicine. Although several animal and cell culture studies have addressed this, human experiments have been limited in their ability to follow changes in specific tissue directly in response to interventions. Recently, methods have allowed for in vivo determination of tissue concentrations and release rates of substances involved in metabolism, inflammation and collagen synthesis, together with the measurement of tissue blood flow and oxygenation in the peritendinous region around the Achilles tendon in humans during exercise. It can be demonstrated that this region experiences an increase in blood flow during both static and dynamic exercise, and that exercise causes increased metabolic activity, accumulation of inflammatory mediators (prostaglandins) and increased formation of collagen type I in response to acute exercise. This coincides with a surprisingly marked drop in tissue pressure during contraction. With regards to both circulation, metabolism and collagen formation, peritendinous tissue represents a dynamic, responsive region that adapts markedly to acute muscular activity.
AB - Soft tissue injury of tendons represents a major problem within sports medicine. Although several animal and cell culture studies have addressed this, human experiments have been limited in their ability to follow changes in specific tissue directly in response to interventions. Recently, methods have allowed for in vivo determination of tissue concentrations and release rates of substances involved in metabolism, inflammation and collagen synthesis, together with the measurement of tissue blood flow and oxygenation in the peritendinous region around the Achilles tendon in humans during exercise. It can be demonstrated that this region experiences an increase in blood flow during both static and dynamic exercise, and that exercise causes increased metabolic activity, accumulation of inflammatory mediators (prostaglandins) and increased formation of collagen type I in response to acute exercise. This coincides with a surprisingly marked drop in tissue pressure during contraction. With regards to both circulation, metabolism and collagen formation, peritendinous tissue represents a dynamic, responsive region that adapts markedly to acute muscular activity.
KW - Achilles Tendon
KW - Adaptation, Physiological
KW - Athletic Injuries
KW - Collagen
KW - Connective Tissue
KW - Exercise
KW - Humans
KW - Inflammation Mediators
KW - Muscle, Skeletal
KW - Oxygen Consumption
KW - Sports
KW - Tendons
M3 - Journal article
C2 - 11085559
VL - 10
SP - 326
EP - 331
JO - Scandinavian Journal of Medicine & Science in Sports
JF - Scandinavian Journal of Medicine & Science in Sports
SN - 0905-7188
IS - 6
ER -
ID: 98570550