In vitro nickel binding to mononuclear cells in peripheral blood
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In vitro nickel binding to mononuclear cells in peripheral blood. / Veien, N K; Morling, N; Svejgaard, E.
In: Acta Dermato Venereologica, Vol. 61, No. 1, 1981, p. 64-6.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - In vitro nickel binding to mononuclear cells in peripheral blood
AU - Veien, N K
AU - Morling, N
AU - Svejgaard, E
N1 - Keywords: Dermatitis, Contact; Humans; Lymphocyte Activation; Nickel
PY - 1981
Y1 - 1981
N2 - Mononuclear cells from the peripheral blood of four nickel-sensitive persons and 4 controls bound equal amounts of 63 nickel in vitro. 90--99% (mean 96%) of the 63 nickel was removed from the cells by washing three times every 30 minutes for 120 minutes. For 4 other patients and 4 controls, lymphocyte transformation with autologous nickel-incubated, irradiated cells as the stimulant showed that nickel was bound to the cells in sufficient quantities and was present in a form which could induce lymphocyte transformation in vitro in nickel-sensitive patients.
AB - Mononuclear cells from the peripheral blood of four nickel-sensitive persons and 4 controls bound equal amounts of 63 nickel in vitro. 90--99% (mean 96%) of the 63 nickel was removed from the cells by washing three times every 30 minutes for 120 minutes. For 4 other patients and 4 controls, lymphocyte transformation with autologous nickel-incubated, irradiated cells as the stimulant showed that nickel was bound to the cells in sufficient quantities and was present in a form which could induce lymphocyte transformation in vitro in nickel-sensitive patients.
M3 - Journal article
C2 - 6164219
VL - 61
SP - 64
EP - 66
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 1
ER -
ID: 18693464