Zach Gerhart-Hines
Associate Professor - Promotion Programme
Gerhart-Hines Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal
2200 København N.
Current research
Signals or cues from the environment, diet, circadian clock, and other organs exert substantial control over the plasticity and function of adipose tissue. The overarching goal of my group is to uncover how these diverse 'inputs' converge on adipocytes to uniquely shape adipose tissue biology and coordinate organismal energy metabolism. Specifically, we focus on identifying cell surface receptors, intracellular enzymes, and transporters that represent key regulatory nodes in influencing adipose tissue catabolism. By combining global gene, protein, metabolite, and lipid profiling with cutting-edge in vivo physiological phenotyping and pharmacological engineering, we believe we are ideally poised to make transformative breakthroughs in the basic understanding of adipose biology and to develop innovative strategies for counteracting metabolic disease.
Possible conflicts of interest
I am a co-founder of Embark Biotech ApS, a company developing therapeutics for the treatment of type 2 diabetes and obesity.
ID: 97571132
Most downloads
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289
downloads
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Research output: Contribution to journal › Journal article › peer-review
Published -
233
downloads
A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
Research output: Contribution to journal › Journal article › peer-review
Published -
218
downloads
Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status
Research output: Contribution to journal › Journal article › peer-review
Published