Sergey Vakhrushev
Associate Professor
Glycomics Program
Blegdamsvej 3
2200 København N.
- 2024
- Published
Global View of Domain-Specific O-Linked Mannose Glycosylation in Glycoengineered Cells
Povolo, Lorenzo, Tian, W., Vakhrushev, Sergey & Halim, Adnan, 2024, In: Molecular & cellular proteomics : MCP. 23, 7, 19 p., 100796.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular-level architecture of Chlamydomonas reinhardtii’s glycoprotein-rich cell wall
Poulhazan, A., Arnold, A. A., Mentink-Vigier, F., Muszyński, A., Azadi, P., Halim, Adnan, Vakhrushev, Sergey, Joshi, Hiren Jitendra, Wang, T., Warschawski, D. E. & Marcotte, I., 2024, In: Nature Communications. 15, 1, 15 p., 986.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting host O-linked glycan biosynthesis affects Ebola virus replication efficiency and reveals differential GalNAc-T acceptor site preferences on the Ebola virus glycoprotein
Bagdonaite, Ieva , Abdurahman, S., Mirandola, M., Pasqual, D., Frank, M., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Vakhrushev, Sergey, Salata, C., Mirazimi, A. & Wandall, Hans H., 2024, In: Journal of Virology. 98, 6, 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution
Chen, Yen-Hsi, Tian, W., Yasuda, M., Ye, Z., Song, Ming, Mandel, Ulla, Kristensen, C., Povolo, Lorenzo, Marques, A. R. A., Čaval, T., Heck, A. J. R., Sampaio, J. L., Johannes, L., Tsukimura, T., Desnick, R., Vakhrushev, Sergey, Yang, Zhang & Clausen, Henrik, 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1128371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of global inhibitors of cellular glycosylation
Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, , 2023, In: Nature Communications. 14, 1, 19 p., 948.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensitive and Specific Global Cell Surface N-Glycoproteomics Shows Profound Differences Between Glycosylation Sites and Subcellular Components
de Haan, Noortje, Song, Ming, Grant, O. C., Ye, Z., Khoder Agha, F., Aasted, Mikkel Koed Møller, Woods, R. J., Vakhrushev, Sergey & Wandall, Hans H., 2023, In: Analytical Chemistry. 95, 47, p. 17328-17336 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated Peptides
Hütte, H. J., Tiemann, B., Shcherbakova, A., Grote, V., Hoffmann, M., Povolo, Lorenzo, Lommel, M., Strahl, S., Vakhrushev, Sergey, Rapp, E., Buettner, F. F. R., Halim, Adnan, Imberty, A. & Bakker, H., 2022, In: Analytical Chemistry. 94, 20, p. 7329–7338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
Coelho, H., Rivas, M. D. L., Grosso, A. S., Diniz, A., Soares, C. O., Francisco, R. A., Dias, J. S., Compañon, I., Sun, L., Narimatsu, Yoshiki, Vakhrushev, Sergey, Clausen, Henrik, Cabrita, E. J., Jiménez-Barbero, J., Corzana, F., Hurtado-Guerrero, R. & Marcelo, F., 2022, In: JACS Au. 2, 3, p. 631-645 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 21237349
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202
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
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135
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A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
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119
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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Research output: Contribution to journal › Journal article › Research › peer-review
Published