Lærke Smidt Gasbjerg
Postdoc, Assistant Professor
Molecular and Translational Pharmacology
Blegdamsvej 3, 2200 København N.
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2024
- E-pub ahead of print
Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge
Gasbjerg, Lærke Smidt, Rasmussen, Rasmus Syberg, Dragan, A., Lindquist, Peter, Melchiorsen, J. U., Stepniewski, T. M., Schiellerup, S., Tordrup, Esther Karen, Gadgaard, S., Kizilkaya, Hüsün Sheyma, Willems, S., Zhong, Y., Wang, Y., Wright, S. C., Lauschke, V. M., Hartmann, Bolette, Holst, Jens Juul, Selent, J. & Rosenkilde, Mette, 2024, (E-pub ahead of print) In: British Journal of Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes
Kizilkaya, H. S., Sørensen, K. V., Madsen, J. S., Lindquist, P., Douros, J. D., Bork-Jensen, J., Berghella, A., Gerlach, P. A., Gasbjerg, L. S., Mokrosiński, J., Mowery, S. A., Knerr, P. J., Finan, B., Campbell, J. E., D’Alessio, D. A., Perez-Tilve, D., Faas, F., Mathiasen, S., Rungby, J., Sørensen, H. T. & 15 others, , 2024, In: Nature Metabolism. 6, p. 1268–1281Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes
Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, In: The Journal of clinical endocrinology and metabolism. 109, 7, p. 1773–1780Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals
Kliim-Hansen, V., Gether, I. M., Juel, C. T., Ellegaard, A., Pedersen, M. G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Lund, Asger Bach, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2024, In: Peptides. 179, 5 p., 171242.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans
Englund, A., Gilliam-Vigh, H., Suppli, M. P., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 7 p., 171227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety of native glucose-dependent insulinotropic polypeptide in humans
Helsted, M. M., Schaltz, N. L., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 14 p., 171214.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glucagon-like peptide 1 in the postprandial effects of metformin in type 2 diabetes: a randomized crossover trial
Hansen, L. S., Gasbjerg, Lærke Smidt, Brønden, Andreas, Dalsgaard, N. B., Bahne, E., Stensen, S., Hellmann, P. H., Rehfeld, Jens Frederik, Hartmann, Bolette, Wever Albrechtsen, N. J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 191, 2, p. 192-203Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two weeks of acarbose treatment shows no effect on gut microbiome composition in patient with type 2 diabetes: a randomised, placebo-controlled, double-blind, crossover study
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Nielsen, Dennis Sandris, Rasmussen, Torben Sølbeck & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 7, 7 p., e240052.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice
Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37775779
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319
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
316
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GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
145
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Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published