Invited Lecture: From Host Defence Peptides to New Antibiotics
Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning
Antimicrobial peptides hold promise as the next generation of antimicrobial agents. However, the potential is weakened by their susceptibility to proteolytic degradation, poor bioavailabillity , toxicity and high cost. Our research interest is in determining the structure/activity relationships of these antimicrobial peptides, which enables us to better understand their mechanism of action and facilitates the development of lead antimicrobial agents. As an example, in this talk I will focus on our work on anoplin and analogues, a decapeptide isolated from the Japanese wasp Anoplius samariensis. I will describe the elucidation of their structure/activity relationships, and our efforts towards developing them into antibiotics.
|Status||Udgivet - 2014|
|Begivenhed||Antibiotic alternatives for the new millennium - London, London, Storbritannien|
Varighed: 5 nov. 2014 → 7 nov. 2014
|Konference||Antibiotic alternatives for the new millennium|
|Periode||05/11/2014 → 07/11/2014|