Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal

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Standard

Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal. / Fazakerley, Daniel J; Fritzen, Andreas Mæchel; Nelson, Marin E; Thorius, Ida H; Cooke, Kristen C; Humphrey, Sean J; Cooney, Gregory J; James, David E.

I: Bio-protocol, Bind 9, Nr. 2, e3146, 2019.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Fazakerley, DJ, Fritzen, AM, Nelson, ME, Thorius, IH, Cooke, KC, Humphrey, SJ, Cooney, GJ & James, DE 2019, 'Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal', Bio-protocol, bind 9, nr. 2, e3146. https://doi.org/10.21769/BioProtoc.3146

APA

Fazakerley, D. J., Fritzen, A. M., Nelson, M. E., Thorius, I. H., Cooke, K. C., Humphrey, S. J., Cooney, G. J., & James, D. E. (2019). Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal. Bio-protocol, 9(2), [e3146]. https://doi.org/10.21769/BioProtoc.3146

Vancouver

Fazakerley DJ, Fritzen AM, Nelson ME, Thorius IH, Cooke KC, Humphrey SJ o.a. Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal. Bio-protocol. 2019;9(2). e3146. https://doi.org/10.21769/BioProtoc.3146

Author

Fazakerley, Daniel J ; Fritzen, Andreas Mæchel ; Nelson, Marin E ; Thorius, Ida H ; Cooke, Kristen C ; Humphrey, Sean J ; Cooney, Gregory J ; James, David E. / Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal. I: Bio-protocol. 2019 ; Bind 9, Nr. 2.

Bibtex

@article{2317c616d38743d091861150dfca45a3,
title = "Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal",
abstract = "Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a risk factor for several metabolic diseases, most notably type 2 diabetes. Insulin resistance occurs in insulin target tissues including liver, adipose and skeletal muscle. Methods such as insulin tolerance tests and hyperinsulinaemic-euglycaemic clamps permit assessment of insulin responses in specific tissues and allow the study of the progression and causes of insulin resistance. Here we detail a protocol for assessing insulin action in adipose and muscle tissues in anesthetized mice administered with insulin intravenously.",
keywords = "Faculty of Science, Insulin, Adipose tissue, Muscle, Glucose transport, Glucose uptake, Insulin tolerance test",
author = "Fazakerley, {Daniel J} and Fritzen, {Andreas M{\ae}chel} and Nelson, {Marin E} and Thorius, {Ida H} and Cooke, {Kristen C} and Humphrey, {Sean J} and Cooney, {Gregory J} and James, {David E}",
note = "CURIS 2019 NEXS 050",
year = "2019",
doi = "10.21769/BioProtoc.3146",
language = "English",
volume = "9",
journal = "Bio-protocol",
issn = "2331-8325",
publisher = "bio-protocol",
number = "2",

}

RIS

TY - JOUR

T1 - Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal

AU - Fazakerley, Daniel J

AU - Fritzen, Andreas Mæchel

AU - Nelson, Marin E

AU - Thorius, Ida H

AU - Cooke, Kristen C

AU - Humphrey, Sean J

AU - Cooney, Gregory J

AU - James, David E

N1 - CURIS 2019 NEXS 050

PY - 2019

Y1 - 2019

N2 - Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a risk factor for several metabolic diseases, most notably type 2 diabetes. Insulin resistance occurs in insulin target tissues including liver, adipose and skeletal muscle. Methods such as insulin tolerance tests and hyperinsulinaemic-euglycaemic clamps permit assessment of insulin responses in specific tissues and allow the study of the progression and causes of insulin resistance. Here we detail a protocol for assessing insulin action in adipose and muscle tissues in anesthetized mice administered with insulin intravenously.

AB - Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a risk factor for several metabolic diseases, most notably type 2 diabetes. Insulin resistance occurs in insulin target tissues including liver, adipose and skeletal muscle. Methods such as insulin tolerance tests and hyperinsulinaemic-euglycaemic clamps permit assessment of insulin responses in specific tissues and allow the study of the progression and causes of insulin resistance. Here we detail a protocol for assessing insulin action in adipose and muscle tissues in anesthetized mice administered with insulin intravenously.

KW - Faculty of Science

KW - Insulin

KW - Adipose tissue

KW - Muscle

KW - Glucose transport

KW - Glucose uptake

KW - Insulin tolerance test

U2 - 10.21769/BioProtoc.3146

DO - 10.21769/BioProtoc.3146

M3 - Journal article

VL - 9

JO - Bio-protocol

JF - Bio-protocol

SN - 2331-8325

IS - 2

M1 - e3146

ER -

ID: 213166605