Age related blood flow around the Achilles tendon during exercise in humans
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Age related blood flow around the Achilles tendon during exercise in humans. / Langberg, Henning; Olesen, J; Skovgaard, D; Kjaer, M.
I: European Journal of Applied Physiology, Bind 84, Nr. 3, 2001, s. 246-8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - Age related blood flow around the Achilles tendon during exercise in humans
AU - Langberg, Henning
AU - Olesen, J
AU - Skovgaard, D
AU - Kjaer, M
PY - 2001
Y1 - 2001
N2 - Injuries due to the overuse of tendons increase with age, and it has been suggested that this correlates with hypovascularity of the tendon. In the present study, the peritendinous blood flow was determined using xenon-133 washout at rest and during standardised intermittent exercise of the calf-muscle (1.5 s contraction, 1.5 s rest, 40 min) in young (n = 6; 26 years), middle-aged (n = 6; 48 years), and older (n = 6; 74 years) individuals. At rest, the older individuals had a lower peritendinous blood flow compared with the two other age groups. During exercise, blood flow in all three groups rose 2.5-3.5-fold to reveal similar blood flows [2.7 (SEM 0.5) to 7.8 (SEM 1.0) ml.100 g tissue-1 min-1 (young group); 3.0 (SEM 0.4) to 7.3 (SEM 1.6) ml.100 g tissue-1 min-1 (middle-aged group); 1.6 (SEM 0.2) to 5.5 (SEM 1.1) ml 100 g tissue-1.min-1 (older group)]. The findings demonstrated that the peritendinous blood flow to the zone of the tendon with the highest incidence of injury from overuse is unaltered by age during exercise, and indicates that factors other than blood flow are important for the increased incidence with age of injuries from overuse.
AB - Injuries due to the overuse of tendons increase with age, and it has been suggested that this correlates with hypovascularity of the tendon. In the present study, the peritendinous blood flow was determined using xenon-133 washout at rest and during standardised intermittent exercise of the calf-muscle (1.5 s contraction, 1.5 s rest, 40 min) in young (n = 6; 26 years), middle-aged (n = 6; 48 years), and older (n = 6; 74 years) individuals. At rest, the older individuals had a lower peritendinous blood flow compared with the two other age groups. During exercise, blood flow in all three groups rose 2.5-3.5-fold to reveal similar blood flows [2.7 (SEM 0.5) to 7.8 (SEM 1.0) ml.100 g tissue-1 min-1 (young group); 3.0 (SEM 0.4) to 7.3 (SEM 1.6) ml.100 g tissue-1 min-1 (middle-aged group); 1.6 (SEM 0.2) to 5.5 (SEM 1.1) ml 100 g tissue-1.min-1 (older group)]. The findings demonstrated that the peritendinous blood flow to the zone of the tendon with the highest incidence of injury from overuse is unaltered by age during exercise, and indicates that factors other than blood flow are important for the increased incidence with age of injuries from overuse.
KW - Achilles Tendon
KW - Adult
KW - Aged
KW - Aging
KW - Exercise
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Muscle Contraction
KW - Muscle, Skeletal
KW - Regional Blood Flow
KW - Rest
U2 - 10.1007/s004210170013
DO - 10.1007/s004210170013
M3 - Journal article
C2 - 11320644
VL - 84
SP - 246
EP - 248
JO - European Journal of Applied Physiology
JF - European Journal of Applied Physiology
SN - 1439-6319
IS - 3
ER -
ID: 38368098