TY - JOUR

T1 - Vitamin d status in patients with chronic obstructive pulmonary disease who participate in pulmonary rehabilitation

AU - Ringbaek, Thomas

AU - Martinez, Gerd

AU - Durakovic, Amal

AU - Thøgersen, Jane

AU - Midjord, Anne-Kirsten

AU - Jensen, Jens-Erik Beck

AU - Lange, Peter

PY - 2011/5/31

Y1 - 2011/5/31

N2 - PURPOSE: Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease; however, no study has evaluated the influence of vitamin D status on effects of pulmonary rehabilitation (PR).METHODS: We studied 311 patients, who participated in a 7-week outpatient PR. Vitamin D status was assessed at entry and examined for association with patient characteristics, dropout from PR, and effect on endurance shuttle walk time.RESULTS: Vitamin D level 25 nM was seen in 61 (19.6%) of the patients. They were significantly younger, were more frequently on long-term oxygen therapy, had higher body mass index and fat-free mass index, had worse quality of life score, tended to have lower percent predicted value for forced expiratory volume in the first second of expiration, and more frequently were current smokers. They had a 3-time higher risk of dropout from the PR program (P = .003) compared with patients with normal vitamin D status and a poorer improvement in endurance shuttle walk time (P = .03).DISCUSSION: In conclusion, vitamin D deficiency was significantly associated with higher dropout rates from PR, and there was a tendency toward a poorer improvement in endurance shuttle walk time.

AB - PURPOSE: Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease; however, no study has evaluated the influence of vitamin D status on effects of pulmonary rehabilitation (PR).METHODS: We studied 311 patients, who participated in a 7-week outpatient PR. Vitamin D status was assessed at entry and examined for association with patient characteristics, dropout from PR, and effect on endurance shuttle walk time.RESULTS: Vitamin D level 25 nM was seen in 61 (19.6%) of the patients. They were significantly younger, were more frequently on long-term oxygen therapy, had higher body mass index and fat-free mass index, had worse quality of life score, tended to have lower percent predicted value for forced expiratory volume in the first second of expiration, and more frequently were current smokers. They had a 3-time higher risk of dropout from the PR program (P = .003) compared with patients with normal vitamin D status and a poorer improvement in endurance shuttle walk time (P = .03).DISCUSSION: In conclusion, vitamin D deficiency was significantly associated with higher dropout rates from PR, and there was a tendency toward a poorer improvement in endurance shuttle walk time.

KW - Aged

KW - Confidence Intervals

KW - Exercise Test

KW - Female

KW - Forced Expiratory Volume

KW - Health Status Indicators

KW - Health Surveys

KW - Humans

KW - Linear Models

KW - Logistic Models

KW - Male

KW - Odds Ratio

KW - Outpatients

KW - Patient Participation

KW - Pulmonary Disease, Chronic Obstructive

KW - Statistics as Topic

KW - Statistics, Nonparametric

KW - Surveys and Questionnaires

KW - Vital Capacity

KW - Vitamin D

KW - Vitamin D Deficiency

U2 - 10.1097/HCR.0b013e31821c13aa

DO - 10.1097/HCR.0b013e31821c13aa

M3 - Journal article

C2 - 21623214

VL - 31

SP - 261

EP - 267

JO - Journal of Cardiopulmonary Rehabilitation and Prevention

JF - Journal of Cardiopulmonary Rehabilitation and Prevention

SN - 1932-7501

IS - 4

ER -