Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder

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Dokumenter

  • Michael Bauer
  • Tasha Glenn
  • Eric D. Achtyes
  • Martin Alda
  • Esen Agaoglu
  • Kürşat Altınbaş
  • Ole A. Andreassen
  • Elias Angelopoulos
  • Raffaella Ardau
  • Edgar Arrua Vares
  • Memduha Aydin
  • Yavuz Ayhan
  • Christopher Baethge
  • Rita Bauer
  • Bernhard T. Baune
  • Ceylan Balaban
  • Claudia Becerra-Palars
  • Aniruddh P. Behere
  • Prakash B. Behere
  • Habte Belete
  • Tilahun Belete
  • Gabriel Okawa Belizario
  • Frank Bellivier
  • Robert H. Belmaker
  • Francesco Benedetti
  • Michael Berk
  • Yuly Bersudsky
  • Şule Bicakci
  • Harriet Birabwa-Oketcho
  • Thomas D. Bjella
  • Conan Brady
  • Jorge Cabrera
  • Marco Cappucciati
  • Angela Marianne Paredes Castro
  • Wei Ling Chen
  • Eric Y.Wo Cheung
  • Silvia Chiesa
  • Marie Crowe
  • Alessandro Cuomo
  • Sara Dallaspezia
  • Maria Del Zompo
  • Pratikkumar Desai
  • Seetal Dodd
  • Markus Donix
  • Bruno Etain
  • Andrea Fagiolini
  • Frederike T. Fellendorf
  • Ewa Ferensztajn-Rochowiak
  • Jess G. Fiedorowicz
  • Kostas N. Fountoulakis
  • Mark A. Frye
  • Pierre A. Geoffroy
  • Ana Gonzalez-Pinto
  • John F. Gottlieb
  • Paul Grof
  • Bartholomeus C.M. Haarman
  • Hirohiko Harima
  • Mathias Hasse-Sousa
  • Chantal Henry
  • Lone Høffding
  • Josselin Houenou
  • Massimiliano Imbesi
  • Erkki T. Isometsä
  • Maja Ivkovic
  • Sven Janno
  • Simon Johnsen
  • Flávio Kapczinski
  • Gregory N. Karakatsoulis
  • Mathias Kardell
  • Seong Jae Kim
  • Barbara König
  • Timur L. Kot
  • Michael Koval
  • Mauricio Kunz
  • Beny Lafer
  • Mikael Landén
  • Melanie Lenger
  • Ute Lewitzka
  • Rasmus W. Licht
  • Carlos Lopez-Jaramillo
  • Alan MacKenzie
  • Helle Østergaard Madsen
  • Simone Alberte Kongstad A. Madsen
  • Jayant Mahadevan
  • Agustine Mahardika
  • Mirko Manchia
  • Wendy Marsh
  • Monica Martinez-Cengotitabengoa
  • Yuki Mashima
  • Declan M. McLoughlin
  • Ybe Meesters
  • Ingrid Melle
  • Fátima Meza-Urzúa
  • Mok Yee Ming
  • Scott Monteith
  • Muthukumaran Moorthy
  • Gunnar Morken
  • Enrica Mosca
  • Anton A. Mozzhegorov
  • Rodrigo Munoz
  • Starlin V. Mythri
  • Fethi Nacef
  • Ravi K. Nadella
  • Takako Nakanotani
  • René Ernst Nielsen
  • Claire O‘Donovan
  • Adel Omrani
  • Yamima Osher
  • Uta Ouali
  • Maja Pantovic-Stefanovic
  • Pornjira Pariwatcharakul
  • Joanne Petite
  • Andrea Pfennig
  • Yolanda Pica Ruiz
  • Maximilian Pilhatsch
  • Marco Pinna
  • Maurizio Pompili
  • Richard Porter
  • Danilo Quiroz
  • Francisco Diego Rabelo-da-Ponte
  • Raj Ramesar
  • Natalie Rasgon
  • Woraphat Ratta-apha
  • Michaela Ratzenhofer
  • Maria Redahan
  • M. S. Reddy
  • Andreas Reif
  • Eva Z. Reininghaus
  • Jenny Gringer Richards
  • Philipp Ritter
  • Janusz K. Rybakowski
  • Leela Sathyaputri
  • Ângela M. Scippa
  • Christian Simhandl
  • Emanuel Severus
  • Daniel Smith
  • José Smith
  • Paul W. Stackhouse
  • Dan J. Stein
  • Kellen Stilwell
  • Sergio Strejilevich
  • Kuan Pin Su
  • Mythily Subramaniam
  • Ahmad Hatim Sulaiman
  • Kirsi Suominen
  • Andi J. Tanra
  • Yoshitaka Tatebayashi
  • Wen Lin Teh
  • Leonardo Tondo
  • Carla Torrent
  • Daniel Tuinstra
  • Takahito Uchida
  • Arne E. Vaaler
  • Julia Veeh
  • Eduard Vieta
  • Biju Viswanath
  • Maria Yoldi-Negrete
  • Oguz Kaan Yalcinkaya
  • Allan H. Young
  • Yosra Zgueb
  • Peter C. Whybrow

Background: Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. Methods: Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun’s electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). Results: This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. Conclusion: A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed.

OriginalsprogEngelsk
Artikelnummer26
TidsskriftInternational Journal of Bipolar Disorders
Vol/bind9
Udgave nummer1
Antal sider14
ISSN2194-7511
DOI
StatusUdgivet - 2021

Bibliografisk note

Funding Information:
Open Access funding enabled and organized by Projekt DEAL. Michael Berk is supported by a NHMRC Senior Principal Research Fellowship (1156072). Pierre A. Geoffroy, Chantal Henry and Josselin Houenou received grants from the French Agence Nationale pour la Recherche (ANR-11-IDEX-0004 Labex BioPsy “Olfaction and Bipolar Disorder” collaborative project, ANR-10-COHO-10–01 psyCOH and ANR-DFG ANR-14-CE35–0035 FUNDO). Mok Yee Ming, Mythily Subramaniam, and Wen Lin Teh received funding from the National Medical Research Centre (NMRC) Centre Grant (Ref No: NMRC/CG/M002/2017_IMH).

Publisher Copyright:
© 2021, The Author(s).

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