Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation. / Rezahosseini, Omid; Drabe, Camilla Heldbjerg; Sørensen, Søren Schwartz; Rasmussen, Allan; Perch, Michael; Ostrowski, Sisse Rye; Nielsen, Susanne Dam.

I: Transplantation Reviews, Bind 33, Nr. 3, 07.2019, s. 137-144.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Rezahosseini, O, Drabe, CH, Sørensen, SS, Rasmussen, A, Perch, M, Ostrowski, SR & Nielsen, SD 2019, 'Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation', Transplantation Reviews, bind 33, nr. 3, s. 137-144. https://doi.org/10.1016/j.trre.2019.03.004

APA

Rezahosseini, O., Drabe, C. H., Sørensen, S. S., Rasmussen, A., Perch, M., Ostrowski, S. R., & Nielsen, S. D. (2019). Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation. Transplantation Reviews, 33(3), 137-144. https://doi.org/10.1016/j.trre.2019.03.004

Vancouver

Rezahosseini O, Drabe CH, Sørensen SS, Rasmussen A, Perch M, Ostrowski SR o.a. Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation. Transplantation Reviews. 2019 jul.;33(3):137-144. https://doi.org/10.1016/j.trre.2019.03.004

Author

Rezahosseini, Omid ; Drabe, Camilla Heldbjerg ; Sørensen, Søren Schwartz ; Rasmussen, Allan ; Perch, Michael ; Ostrowski, Sisse Rye ; Nielsen, Susanne Dam. / Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation. I: Transplantation Reviews. 2019 ; Bind 33, Nr. 3. s. 137-144.

Bibtex

@article{e4b89d0795a04e77b4114eb5b7dbdfa9,
title = "Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation",
abstract = "Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid rejection of the transplanted organ. Immunosuppressive therapy increases the risk of infections. However, no existing marker reliably reveals the status of the immune function in SOT recipients. Torque-Teno virus or Transfusion-transmitted virus (TTV) has gained attention as a possible endogenous marker of the immune function. TTV is a non-enveloped, circular single strand DNA virus, and it may be considered a part of the human virome. In a bidirectional relationship, the immune system detects TTV and TTV may also modulate the activity of immune system. These characteristics have made the virus a possible candidate indicator of immune function. In this systematic review, we describe the role and potential function of TTV viral load as an endogenous marker of the immune function and consequently the level of immune suppression in SOT recipients.",
keywords = "Immunosuppression, Infection, Organ transplantation, Rejection, Torque Teno virus",
author = "Omid Rezahosseini and Drabe, {Camilla Heldbjerg} and S{\o}rensen, {S{\o}ren Schwartz} and Allan Rasmussen and Michael Perch and Ostrowski, {Sisse Rye} and Nielsen, {Susanne Dam}",
year = "2019",
month = jul,
doi = "10.1016/j.trre.2019.03.004",
language = "English",
volume = "33",
pages = "137--144",
journal = "Transplantation Reviews",
issn = "0955-470X",
publisher = "W.B.Saunders Co.",
number = "3",

}

RIS

TY - JOUR

T1 - Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

AU - Rezahosseini, Omid

AU - Drabe, Camilla Heldbjerg

AU - Sørensen, Søren Schwartz

AU - Rasmussen, Allan

AU - Perch, Michael

AU - Ostrowski, Sisse Rye

AU - Nielsen, Susanne Dam

PY - 2019/7

Y1 - 2019/7

N2 - Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid rejection of the transplanted organ. Immunosuppressive therapy increases the risk of infections. However, no existing marker reliably reveals the status of the immune function in SOT recipients. Torque-Teno virus or Transfusion-transmitted virus (TTV) has gained attention as a possible endogenous marker of the immune function. TTV is a non-enveloped, circular single strand DNA virus, and it may be considered a part of the human virome. In a bidirectional relationship, the immune system detects TTV and TTV may also modulate the activity of immune system. These characteristics have made the virus a possible candidate indicator of immune function. In this systematic review, we describe the role and potential function of TTV viral load as an endogenous marker of the immune function and consequently the level of immune suppression in SOT recipients.

AB - Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid rejection of the transplanted organ. Immunosuppressive therapy increases the risk of infections. However, no existing marker reliably reveals the status of the immune function in SOT recipients. Torque-Teno virus or Transfusion-transmitted virus (TTV) has gained attention as a possible endogenous marker of the immune function. TTV is a non-enveloped, circular single strand DNA virus, and it may be considered a part of the human virome. In a bidirectional relationship, the immune system detects TTV and TTV may also modulate the activity of immune system. These characteristics have made the virus a possible candidate indicator of immune function. In this systematic review, we describe the role and potential function of TTV viral load as an endogenous marker of the immune function and consequently the level of immune suppression in SOT recipients.

KW - Immunosuppression

KW - Infection

KW - Organ transplantation

KW - Rejection

KW - Torque Teno virus

U2 - 10.1016/j.trre.2019.03.004

DO - 10.1016/j.trre.2019.03.004

M3 - Review

C2 - 30981537

AN - SCOPUS:85064073378

VL - 33

SP - 137

EP - 144

JO - Transplantation Reviews

JF - Transplantation Reviews

SN - 0955-470X

IS - 3

ER -

ID: 240626821