The effect of sertindole on QTD and TPTE
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The effect of sertindole on QTD and TPTE. / Nielsen, J; Andersen, M P; Graff, Claus; Kanters, Jørgen K.; Hardahl, Thomas Bork; Dybbro, J; Struijk, Johannes J.; Meyer, J M; Toft, E.
I: Acta Psychiatrica Scandinavica. Supplementum, Bind 121, Nr. 5, 01.05.2010, s. 385-8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The effect of sertindole on QTD and TPTE
AU - Nielsen, J
AU - Andersen, M P
AU - Graff, Claus
AU - Kanters, Jørgen K.
AU - Hardahl, Thomas Bork
AU - Dybbro, J
AU - Struijk, Johannes J.
AU - Meyer, J M
AU - Toft, E
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Recent research suggests that other surrogate markers than QTc, including QTc dispersion and Tpeak-Tend, may better correlate with cardiac arrhythmia risk. While sertindole significantly prolongs the QTc interval, the effects on other markers of arrhythmia risk, such as QTc dispersion and Tpeak-Tend are unknown.
AB - Recent research suggests that other surrogate markers than QTc, including QTc dispersion and Tpeak-Tend, may better correlate with cardiac arrhythmia risk. While sertindole significantly prolongs the QTc interval, the effects on other markers of arrhythmia risk, such as QTc dispersion and Tpeak-Tend are unknown.
KW - Adult
KW - Antipsychotic Agents
KW - Denmark
KW - Electrocardiography
KW - Female
KW - Heart Rate
KW - Humans
KW - Imidazoles
KW - Indoles
KW - Long QT Syndrome
KW - Male
KW - Middle Aged
KW - Prospective Studies
KW - Safety-Based Drug Withdrawals
KW - Schizophrenia
KW - Signal Processing, Computer-Assisted
KW - Torsades de Pointes
U2 - 10.1111/j.1600-0447.2009.01534.x
DO - 10.1111/j.1600-0447.2009.01534.x
M3 - Journal article
C2 - 20085555
VL - 121
SP - 385
EP - 388
JO - Acta Psychiatrica Scandinavica. Supplementum
JF - Acta Psychiatrica Scandinavica. Supplementum
SN - 0065-1591
IS - 5
ER -
ID: 33910959