The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea. / Kim, Woosung; Jang, Yoonyoung; Lim, Youn-Hee; Kim, Bung-Nyun; Shin, Choong Ho; Lee, Young Ah; Kim, Johanna Inhyang; Hong, Yun-Chul.
I: Journal of Preventive Medicine and Public Health, Bind 53, Nr. 1, 2020, s. 29-36.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea
AU - Kim, Woosung
AU - Jang, Yoonyoung
AU - Lim, Youn-Hee
AU - Kim, Bung-Nyun
AU - Shin, Choong Ho
AU - Lee, Young Ah
AU - Kim, Johanna Inhyang
AU - Hong, Yun-Chul
PY - 2020
Y1 - 2020
N2 - OBJECTIVES: Prenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation and ADHD at 6 years of age.METHODS: As part of an ongoing cohort study (the Environment and Development of Children study), 479 mother-child pairs from Seoul, Korea were included for analysis between 2008 and 2011. The whole blood concentration of Cd was analyzed using atomic absorption spectrophotometry. The parents were surveyed about ADHD behaviors in their children at age 6. Multivariable linear regression models were used to investigate the relationship between prenatal exposure to Cd and ADHD at 6 years of age.RESULTS: Increased prenatal Cd concentrations were associated with increased scores for ADHD for girls, but not for boys, at age 6. A 2-fold increase in the prenatal Cd level was significantly associated with a 22.3% (95% confidence interval, 11.6 to 34.1) increase in ADHD in girls at 6 years of age, as indicated by the linear regression model.CONCLUSIONS: Our results identified significant associations between prenatal Cd exposure and ADHD scores in 6-year-old girls.
AB - OBJECTIVES: Prenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation and ADHD at 6 years of age.METHODS: As part of an ongoing cohort study (the Environment and Development of Children study), 479 mother-child pairs from Seoul, Korea were included for analysis between 2008 and 2011. The whole blood concentration of Cd was analyzed using atomic absorption spectrophotometry. The parents were surveyed about ADHD behaviors in their children at age 6. Multivariable linear regression models were used to investigate the relationship between prenatal exposure to Cd and ADHD at 6 years of age.RESULTS: Increased prenatal Cd concentrations were associated with increased scores for ADHD for girls, but not for boys, at age 6. A 2-fold increase in the prenatal Cd level was significantly associated with a 22.3% (95% confidence interval, 11.6 to 34.1) increase in ADHD in girls at 6 years of age, as indicated by the linear regression model.CONCLUSIONS: Our results identified significant associations between prenatal Cd exposure and ADHD scores in 6-year-old girls.
U2 - 10.3961/jpmph.19.175
DO - 10.3961/jpmph.19.175
M3 - Journal article
C2 - 32023672
VL - 53
SP - 29
EP - 36
JO - Journal of Preventive Medicine and Public Health
JF - Journal of Preventive Medicine and Public Health
SN - 1975-8375
IS - 1
ER -
ID: 236262832