Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

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Standard

Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection. / Rønn, S G; Börjesson, A; Bruun, C; Heding, P E; Frobøse, H; Mandrup-Poulsen, T; Karlsen, A E; Rasschaert, J; Sandler, S; Billestrup, Nils.

I: Diabetologia, Bind 51, Nr. 10, 2008, s. 1873-1882.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Rønn, SG, Börjesson, A, Bruun, C, Heding, PE, Frobøse, H, Mandrup-Poulsen, T, Karlsen, AE, Rasschaert, J, Sandler, S & Billestrup, N 2008, 'Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection', Diabetologia, bind 51, nr. 10, s. 1873-1882. https://doi.org/10.1007/s00125-008-1090-0

APA

Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, T., Karlsen, A. E., Rasschaert, J., Sandler, S., & Billestrup, N. (2008). Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection. Diabetologia, 51(10), 1873-1882. https://doi.org/10.1007/s00125-008-1090-0

Vancouver

Rønn SG, Börjesson A, Bruun C, Heding PE, Frobøse H, Mandrup-Poulsen T o.a. Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection. Diabetologia. 2008;51(10):1873-1882. https://doi.org/10.1007/s00125-008-1090-0

Author

Rønn, S G ; Börjesson, A ; Bruun, C ; Heding, P E ; Frobøse, H ; Mandrup-Poulsen, T ; Karlsen, A E ; Rasschaert, J ; Sandler, S ; Billestrup, Nils. / Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection. I: Diabetologia. 2008 ; Bind 51, Nr. 10. s. 1873-1882.

Bibtex

@article{1ce2b210de5811ddb5fc000ea68e967b,
title = "Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection",
abstract = "The pro-inflammatory cytokines IL-1 and IFNgamma are critical molecules in immune-mediated beta cell destruction leading to type 1 diabetes mellitus. Suppressor of cytokine signalling (SOCS)-3 inhibits the cytokine-mediated destruction of insulinoma-1 cells. Here we investigate the effect of SOCS3 in primary rodent beta cells and diabetic animal models.",
keywords = "Alloxan, Animals, Animals, Newborn, Apoptosis, Blotting, Western, Cytokines, Diabetes Mellitus, Experimental, Graft Survival, Humans, In Situ Nick-End Labeling, Islets of Langerhans, Islets of Langerhans Transplantation, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Rats, Reverse Transcriptase Polymerase Chain Reaction, Suppressor of Cytokine Signaling Proteins, Transplantation, Homologous",
author = "R{\o}nn, {S G} and A B{\"o}rjesson and C Bruun and Heding, {P E} and H Frob{\o}se and T Mandrup-Poulsen and Karlsen, {A E} and J Rasschaert and S Sandler and Nils Billestrup",
year = "2008",
doi = "10.1007/s00125-008-1090-0",
language = "English",
volume = "51",
pages = "1873--1882",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "10",

}

RIS

TY - JOUR

T1 - Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

AU - Rønn, S G

AU - Börjesson, A

AU - Bruun, C

AU - Heding, P E

AU - Frobøse, H

AU - Mandrup-Poulsen, T

AU - Karlsen, A E

AU - Rasschaert, J

AU - Sandler, S

AU - Billestrup, Nils

PY - 2008

Y1 - 2008

N2 - The pro-inflammatory cytokines IL-1 and IFNgamma are critical molecules in immune-mediated beta cell destruction leading to type 1 diabetes mellitus. Suppressor of cytokine signalling (SOCS)-3 inhibits the cytokine-mediated destruction of insulinoma-1 cells. Here we investigate the effect of SOCS3 in primary rodent beta cells and diabetic animal models.

AB - The pro-inflammatory cytokines IL-1 and IFNgamma are critical molecules in immune-mediated beta cell destruction leading to type 1 diabetes mellitus. Suppressor of cytokine signalling (SOCS)-3 inhibits the cytokine-mediated destruction of insulinoma-1 cells. Here we investigate the effect of SOCS3 in primary rodent beta cells and diabetic animal models.

KW - Alloxan

KW - Animals

KW - Animals, Newborn

KW - Apoptosis

KW - Blotting, Western

KW - Cytokines

KW - Diabetes Mellitus, Experimental

KW - Graft Survival

KW - Humans

KW - In Situ Nick-End Labeling

KW - Islets of Langerhans

KW - Islets of Langerhans Transplantation

KW - Mice

KW - Mice, Inbred C57BL

KW - Mice, Inbred NOD

KW - Mice, Transgenic

KW - Rats

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Suppressor of Cytokine Signaling Proteins

KW - Transplantation, Homologous

U2 - 10.1007/s00125-008-1090-0

DO - 10.1007/s00125-008-1090-0

M3 - Journal article

C2 - 18648765

VL - 51

SP - 1873

EP - 1882

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 10

ER -

ID: 9618268