Sleep disturbances in IDDM patients with nocturnal hypoglycemia.
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Sleep disturbances in IDDM patients with nocturnal hypoglycemia. / Bendtson, I; Gade, J; Thomsen, C E; Rosenfalck, A; Wildschiødtz, G.
I: Sleep, Bind 15, Nr. 1, 1992, s. 74-81.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Sleep disturbances in IDDM patients with nocturnal hypoglycemia.
AU - Bendtson, I
AU - Gade, J
AU - Thomsen, C E
AU - Rosenfalck, A
AU - Wildschiødtz, G
N1 - Keywords: Adult; Blood Glucose; Cerebral Cortex; Diabetes Mellitus, Type 1; Electroencephalography; Growth Hormone; Humans; Hypoglycemia; Male; Middle Aged; Monitoring, Physiologic; Reaction Time; Signal Processing, Computer-Assisted; Sleep Stages; Sleep, REM
PY - 1992
Y1 - 1992
N2 - Eight insulin-dependent diabetic patients were studied to evaluate sleep patterns during normoglycemia and spontaneous and insulin-induced hypoglycemia. Two channels of electroencephalogram (EEG), electromyogram and actooculogram were recorded. The signals were analyzed off-line, using a polygraphic sleep analysis system. The scoring was mainly based on the color density spectral array of the EEG. Blood glucose and growth hormone were measured serially. Asymptomatic, spontaneous nocturnal hypoglycemia occurred in 38% of the nights. Conventional sleep analysis showed a tendency toward prolongation of the two first rapid eye movement cycles on hypoglycemic nights, although it was insufficient to explain the activities seen during hypoglycemia. Blood glucose values below 2.0 mmol/l were observed in some of the patients accompanied by EEG changes with increased theta and delta activity.
AB - Eight insulin-dependent diabetic patients were studied to evaluate sleep patterns during normoglycemia and spontaneous and insulin-induced hypoglycemia. Two channels of electroencephalogram (EEG), electromyogram and actooculogram were recorded. The signals were analyzed off-line, using a polygraphic sleep analysis system. The scoring was mainly based on the color density spectral array of the EEG. Blood glucose and growth hormone were measured serially. Asymptomatic, spontaneous nocturnal hypoglycemia occurred in 38% of the nights. Conventional sleep analysis showed a tendency toward prolongation of the two first rapid eye movement cycles on hypoglycemic nights, although it was insufficient to explain the activities seen during hypoglycemia. Blood glucose values below 2.0 mmol/l were observed in some of the patients accompanied by EEG changes with increased theta and delta activity.
M3 - Journal article
C2 - 1557597
VL - 15
SP - 74
EP - 81
JO - Sleep (Online)
JF - Sleep (Online)
SN - 0161-8105
IS - 1
ER -
ID: 5941950