Short- and long-term mortality and causes of death in HIV/tuberculosis patients in Europe

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Podlekareva, Daria
  • Alexander M Panteleev
  • Daniel Grint
  • Frank A Post
  • Jose M Miro
  • Mathias Bruyand
  • Hansjakob Furrer
  • Obel, Niels
  • Enrico Girardi
  • Anna Vasilenko
  • Marcelo H Losso
  • Alejandro Arenas-Pinto
  • Joan Caylá
  • Aza Rakhmanova
  • Indra Zeltina
  • Anne Marie Werlinrud
  • Lundgren, Jens
  • Amanda Mocroft
  • Kirk, Ole
  • HIV/TB study group
Mortality of HIV/tuberculosis (TB) patients in Eastern Europe is high. Little is known about their causes of death. This study aimed to assess and compare mortality rates and cause of death in HIV/TB patients across Eastern Europe and Western Europe and Argentina (WEA) in an international cohort study. Mortality rates and causes of death were analysed by time from TB diagnosis (12 months) in 1078 consecutive HIV/TB patients. Factors associated with TB-related death were examined in multivariate Poisson regression analysis. 347 patients died during 2625 person-years of follow-up. Mortality in Eastern Europe was three- to ninefold higher than in WEA. TB was the main cause of death in Eastern Europe in 80%, 66% and 61% of patients who died 12 months after TB diagnosis, compared to 50%, 0% and 15% in the same time periods in WEA (p
TidsskriftEuropean Respiratory Journal
Udgave nummer1
Sider (fra-til)166-77
Antal sider12
StatusUdgivet - jan. 2014

ID: 105611928