The reactivity of solid particles of two forms of TiO₂, rutile and anatase, with H₂O₂ vapour was investigated for use as reactive coatings protecting granular formulations of enzymes. Reactivity tests using potassium titanium oxide oxalate as a competition probe showed a high reactivity of anatase at both high and low H₂O₂ pressure, whereas rutile was moderately reactive only at high H₂O₂ pressure. Heating H₂O₂-treated rutile and anatase led to release of oxygen, but not of surface-bound H₂O₂. For rutile, electron spin resonance measurements showed formation of radical intermediates. Anatase showed a mechanism comprising reversible binding of H₂O₂ and catalytic cleavage of H₂O₂ without formation of radicals. Anatase-coated detergent enzyme granules confirmed the protection against H₂O₂ vapour. Overall, this work shows the potential of anatase as a reactive coating material in laundry granules as an alternative to the current formulation.