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Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics. / Rigoni, Lorenzo; Venti, Sara; Bevilacqua, Marta; Bucci, Remo; Magrì, Andrea D.; Magrì, Antonio L.; Marini, Federico.
I:
Chemometrics and Intelligent Laboratory Systems, Bind 133, 2014, s. 149 - 156.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › fagfællebedømt
Harvard
Rigoni, L, Venti, S
, Bevilacqua, M, Bucci, R, Magrì, AD, Magrì, AL & Marini, F 2014, '
Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics',
Chemometrics and Intelligent Laboratory Systems, bind 133, s. 149 - 156.
https://doi.org/10.1016/j.chemolab.2014.02.004
APA
Rigoni, L., Venti, S.
, Bevilacqua, M., Bucci, R., Magrì, A. D., Magrì, A. L., & Marini, F. (2014).
Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics.
Chemometrics and Intelligent Laboratory Systems,
133, 149 - 156.
https://doi.org/10.1016/j.chemolab.2014.02.004
Vancouver
Rigoni L, Venti S
, Bevilacqua M, Bucci R, Magrì AD, Magrì AL o.a.
Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics.
Chemometrics and Intelligent Laboratory Systems. 2014;133:149 - 156.
https://doi.org/10.1016/j.chemolab.2014.02.004
Author
Rigoni, Lorenzo ; Venti, Sara ; Bevilacqua, Marta ; Bucci, Remo ; Magrì, Andrea D. ; Magrì, Antonio L. ; Marini, Federico. / Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics. I: Chemometrics and Intelligent Laboratory Systems. 2014 ; Bind 133. s. 149 - 156.
Bibtex
@article{0dd9dc57702a46f390c99bd5f5426e56,
title = "Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics",
abstract = "A method for the quantification of the enantiomeric excess of two pharmaceutical active ingredients (ibuprofen and epinephrine) in the solid state based on coupling near infrared spectroscopy and chemometrics is proposed. In the case of ibuprofen, in the absence of excipients, the method resulted in an accurate prediction of the enantiopurity of the validation samples (RMSEP ",
keywords = "Enantiomeric excess, Near infrared spectroscopy (NIR), Ibuprofen, Epinephrine, Partial least squares (PLS) regression",
author = "Lorenzo Rigoni and Sara Venti and Marta Bevilacqua and Remo Bucci and Magr{\`i}, {Andrea D.} and Magr{\`i}, {Antonio L.} and Federico Marini",
year = "2014",
doi = "10.1016/j.chemolab.2014.02.004",
language = "English",
volume = "133",
pages = "149 -- 156",
journal = "Chemometrics and Intelligent Laboratory Systems",
issn = "0169-7439",
publisher = "Elsevier",
}
RIS
TY - JOUR
T1 - Quantification of the enantiomeric excess of two APIs by means of near infrared spectroscopy and chemometrics
AU - Rigoni, Lorenzo
AU - Venti, Sara
AU - Bevilacqua, Marta
AU - Bucci, Remo
AU - Magrì, Andrea D.
AU - Magrì, Antonio L.
AU - Marini, Federico
PY - 2014
Y1 - 2014
N2 - A method for the quantification of the enantiomeric excess of two pharmaceutical active ingredients (ibuprofen and epinephrine) in the solid state based on coupling near infrared spectroscopy and chemometrics is proposed. In the case of ibuprofen, in the absence of excipients, the method resulted in an accurate prediction of the enantiopurity of the validation samples (RMSEP
AB - A method for the quantification of the enantiomeric excess of two pharmaceutical active ingredients (ibuprofen and epinephrine) in the solid state based on coupling near infrared spectroscopy and chemometrics is proposed. In the case of ibuprofen, in the absence of excipients, the method resulted in an accurate prediction of the enantiopurity of the validation samples (RMSEP
KW - Enantiomeric excess
KW - Near infrared spectroscopy (NIR)
KW - Ibuprofen
KW - Epinephrine
KW - Partial least squares (PLS) regression
U2 - 10.1016/j.chemolab.2014.02.004
DO - 10.1016/j.chemolab.2014.02.004
M3 - Journal article
VL - 133
SP - 149
EP - 156
JO - Chemometrics and Intelligent Laboratory Systems
JF - Chemometrics and Intelligent Laboratory Systems
SN - 0169-7439
ER -